Protein Alignment app and Hip14

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001261910.1
• Gene: Hip14 / 39747
• FlyBaseID: FBgn0259824
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 85/329 - (25%)
• Similarity: 131/329 - (39%)
• Gaps: 100/329 - (30%)

  Fly    30 KFYCDGLLMSAPHT---GVF--YLTCIL----ITGTSALFFAFDCPFLADSINPAIPIVGAVLYF 85
            ||:..|.|.|..||   .:|  :|..:|    ...|.|.|:.....::.|:::     ..|.:.|
  Fly   323 KFFLLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYVTWLMYIDDAVS-----FTATVCF 382

  Fly    86 FTMSSLLRTTFT-----DPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVK 145
            ...|.||...|.     |||:| |.:.::                       |.|.::...:...
  Fly   383 LISSLLLWVCFLKSWKGDPGII-RPTREQ-----------------------RFKTIIELSERGG 423

  Fly   146 L-----KYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAV- 204
            :     .:|..|.:.||.|:.|||:||.||.||||||||||||:|.:|:.:|..||..|..:..
  Fly   424 IGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAW 488

  Fly   205 --------FIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFH------ 255
                    ::..|:|        :..:....::|       :..|...:..|:|.|..|
  Fly   489 MLYGGSKYYVNQCNV--------RFDDFLGAMRA-------IGNCDAWVGWVMGNALLHMSWVIL 538

  Fly   256 -----TY-LTTSDQTTNEDLKGS----FSSKGGPRTQNPYSRGNI-----CLNCCHILC-GPMTP 304
                 || :.....||||.:...    |.:|||   .:|::||.|     .|.|.   | |.:.|
  Fly   539 LTICQTYQVICLGMTTNERMNRGRYRHFQAKGG---HSPFTRGPIQNLVDFLECS---CFGLVQP 597

  Fly   305 SLID 308
            ..:|
  Fly   598 KRVD 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	44/149 (30%)
Hip14	NP_001261910.1	ANKYR	<52..246	CDD:440430
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		ANK repeat	212..244	CDD:293786
		DHHC	426..559	CDD:396215	44/147 (30%)