Protein Alignment app and Zdhhc13

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001382044.1
• Gene: Zdhhc13 / 365252
• RGDID: 1309736
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 71/301 - (23%)
• Similarity: 119/301 - (39%)
• Gaps: 80/301 - (26%)

  Fly    45 VFYLTCILITGTSALFFAFDCPFLADSINPA-----IPIVGAVLYFFTMSSLLRTTFTDPGVIPR 104
            |:..|..|::....:|..:...|..|:....     |..:.|.||||     .:|..|||| ..:
  Rat   345 VYLPTVFLLSSIFWIFMTWFILFFPDAAGSPFYFAFIFSIMAFLYFF-----YKTWATDPG-FTK 403

  Fly   105 ASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKL---KYCFTCKIFRPPRASHCSLC 166
            ||.:|                       |...::...:|..|   .:|.:|.|.:|.|:.||.:|
  Rat   404 ASEEE-----------------------RKVNIVTLAETGSLDFRTFCTSCLIRKPLRSLHCHVC 445

  Fly   167 DNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIF---------SCSVTHLVLLMKKEH 222
            ::||.|||.||.|.|.|:|..|:..:..||:||:.:..:|.         .|:.|.      ||.
  Rat   446 NSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWSNHCATTF------KED 504

  Fly   223 EVF----NVIKAAPFTVIVVFICFFSI-WSV---------IGLAGFHTYLTTSDQTTNEDLKGSF 273
            .::    .::..:|:.:.:..:..|.. ||.         |...|..::...|....:..:|.:.
  Rat   505 GLWTYLNQIVACSPWVLYIFMLAAFHFSWSTFLLINQLFQIAFLGLTSHERISLLKQSRHMKQTL 569

  Fly   274 SSKGGPRTQNPYSRG---NIC--LNC-CHILCGPMTPSLID 308
            |.:     :.||:.|   |:.  ..| |.   |.:.|.:||
  Rat   570 SLR-----KTPYNLGFMQNLADFFQCGCF---GLVKPCIID 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	37/149 (25%)
Zdhhc13	NP_001382044.1	ANKYR	29..289	CDD:440430
		ANK repeat	81..112	CDD:293786
		ANK repeat	114..146	CDD:293786
		ANK repeat	148..179	CDD:293786
		ANK repeat	181..247	CDD:293786
		DHHC	423..557	CDD:396215	35/139 (25%)