Protein Alignment app and Zdhhc18

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_038966311.1
• Gene: Zdhhc18 / 362613
• RGDID: 1309334
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 221/482 - (45%)
• Similarity: 289/482 - (59%)
• Gaps: 72/482 - (14%)

  Fly    16 QRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVG 80
            :|..||||:|.|||:|||.|.||.|.|.|||.||.:||..|:.|||.||||:||.::..||||:.
  Rat    62 RRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILSTTILFFIFDCPYLARTLTLAIPIIA 126

  Fly    81 AVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVK 145
            |:|:||.||.||:|:|||||::|||:..|||.:||||:   :..|.||||||||:||::.||.||
  Rat   127 AILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQID---NTGSSTYRPPPRTREVMINGQMVK 188

  Fly   146 LKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCS 210
            ||||||||:|||||.||||:|||||:||||||||||||||:|||||||.|::||:||..|||:|.
  Rat   189 LKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACV 253

  Fly   211 VTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSS 275
            ||||.||.:..: ..:.:|..|.:|:.:.||||||||::||:||||||..|:.|||||:|||:||
  Rat   254 VTHLTLLSQGSN-FLSALKKTPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS 317

  Fly   276 K-GGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASH 339
            | ||..:.||||..:|..|||.:||||:.||||||||     |:|......||
  Rat   318 KRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRG-----FVQSDTVLPSP------------ 365

  Fly   340 MVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFD 404
             :.:.:|..|                            :.|.:|...|..|....|.:.......
  Rat   366 -IRSDEPACG----------------------------AKPDASMAPGLRGVRRTHPSLDLEASS 401

  Fly   405 HPPPSYDLVQN----------GKSRKHHQQRCSLQTLLPASAQQQFKASKHKHKQLKQHLVAAEL 459
            .|.|...|:.:          ||.|...:.|.:||.      :::|.:.|.:.:.|   |....|
  Rat   402 LPSPRSRLLVSWDFQVAPQDLGKPRPGWEPRKALQD------REEFSSWKGRSRCL---LYLTVL 457

  Fly   460 QQHEGGPGPGPNSPSLLRSPATSSSYR 486
            ....|  ..|..:||||.:|..::..|
  Rat   458 SVWRG--KFGLRTPSLLWTPGQTTGDR 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	83/123 (67%)
Zdhhc18	XP_038966311.1	DHHC	189..312	CDD:396215	83/123 (67%)