Protein Alignment app and ZDHHC21

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001341047.1
• Gene: ZDHHC21 / 340481
• HGNCID: 20750
• Length: 265
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 73/282 - (25%)
• Similarity: 113/282 - (40%)
• Gaps: 79/282 - (28%)

  Fly    33 CDGLLMSAPHTGVF-YLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLY---FFTMSSLLR 93
            |.||:       || :|..|::.....||     |...:...|.|.|:  :.|   .|.:.:|:|
Human    16 CMGLI-------VFVWLYNIVLIPKIVLF-----PHYEEGHIPGILII--IFYGISIFCLVALVR 66

  Fly    94 TTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPP 158
            .:.||||.:|           :..::|:                   |:....:.|..|.:.||.
Human    67 ASITDPGRLP-----------ENPKIPH-------------------GEREFWELCNKCNLMRPK 101

  Fly   159 RASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFF--YLFLVSLAFLAVFIFS-CSVTHLVLLMKK 220
            |:.|||.|.:||.|.||||||:.||||:.|:..|  ..|...|......:|| |...:.:.|.|:
Human   102 RSHHCSRCGHCVRRMDHHCPWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLPLKKR 166

  Fly   221 EHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAG-FHTYL--TTSDQTTNEDLKGSFSSKGGPRTQ 282
            ..::| |.:..  ..|:....|..|..::|:.| |:|.|  ..:|.|:.|.:.
Human   167 NLDLF-VFRHE--LAIMRLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMS------------ 216

  Fly   283 NPYSRGNICLNCCHILCGPMTP 304
                      |||..:..|..|
Human   217 ----------NCCEDISRPRKP 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	44/129 (34%)
ZDHHC21	NP_001341047.1	DHHC	92..217	CDD:396215	44/149 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810