Protein Alignment app and CG17075

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001245821.1
• Gene: CG17075 / 33191
• FlyBaseID: FBgn0031239
• Length: 968
• Species: Drosophila melanogaster
• Alignment Length: 930
• Identity: 179/930 - (19%)
• Similarity: 278/930 - (29%)
• Gaps: 354/930 - (38%)

  Fly    10 SNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP 74
            ||:|..|.  ||     ||.   ..||.:......:|....:|:.|.::.:      .|..:.:.
  Fly    90 SNIADVQH--RK-----GRR---LHGLQLPLHPLQIFGWLVLLLFGVASYW------VLIPAFHA 138

  Fly    75 AI--PIVGAV--LYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTK 135
            .|  |:.|.:  ||...::|.|....|||      ::.|...:.:     |....|.:   .|:|
  Fly   139 RIQGPLYGLITGLYLVHIASHLTALLTDP------ADKELRRVHR-----NDRIVPEF---DRSK 189

  Fly   136 --EVLVKGQTVKLKYCFTCKI-FRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLV 197
              .|:..|:      |..|.| ....|..|||:|:.||.:|||||.|:.:|:|.|||..|.:.:|
  Fly   190 HSHVIENGR------CHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVV 248

  Fly   198 SLAFLAVFIFSCSVTHLV--------------------------------------LLMKKEH-- 222
            |.....:.|.:..|..:|                                      :::.::|
  Fly   249 SAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITLSLSNGTMMLIEQHTS 313

  Fly   223 ------EVFN------VIKAAP-----FTVIV--------------------------------- 237
                  |:::      .|...|     ||.|:
  Fly   314 EEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQPVVTGIGLNETIFMF 378

  Fly   238 ----------------VFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYS 286
                            :.:|||.|:  |...|..||....:....:|.|.....:|.|..:.| .
  Fly   379 LLGVLGLLAAVSAGLLLHLCFFHIY--ISFLGLTTYEYIRNHRQAQDAKTKQLLEGAPGVRAP-K 440

  Fly   287 RGNI------------------------C----------------------LNCC---------- 295
            .||:                        |                      |:||
  Fly   441 NGNVHFSASLPEPHNPSKSLPGGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFHQSG 505

  Fly   296 --------------------------HILCGPMTPSLIDRR-GIATDEFIQQMQHQSSPRHALSD 333
                                      | .|.....|.:.|| .:|....|     .:.|||
  Fly   506 QAIYVCSLLEEAVPQIQVEPDTLSSFH-CCSSFAASSLQRRVSLAKGSLI-----SAEPRH---- 560

  Fly   334 VLSASHMVTTSQPMMGGL-----GGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAIN 393
            :..|:::..|.|..:...     .|.|.|.:|...|.||:.           |:.||....|..:
  Fly   561 LRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSS-----------STRTLTSQTGGSS 614

  Fly   394 GHGNGHGNGFDHP------------PPSYDLVQNGKSRKHHQQRCSLQTLLPASAQQQFKASKHK 446
            ......||...|.            |.|.||..:           .|..|....:::...|:|..
  Fly   615 ASATAAGNISKHQRWRRKWNCCAAVPDSPDLPND-----------LLAALTFRESEEAAAAAKLN 668

  Fly   447 HKQLKQHLVAA-------ELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLTPSYDDV 504
            .::|....:..       ||........|.|...|.||       |.|.|......|      ..
  Fly   669 AQELPIQFIRTLNGGLDQELPLKATTATPTPPRSSRLR-------YMLRLLGRYRRP------RC 720

  Fly   505 RHSPLPLLHHHVHAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTTAPTS------ 563
            ||.    .||.:.|::...||     .:|:.............|.|.::|:||.|.|.|
  Fly   721 RHG----AHHGIAAKEHQNIG-----GSAIKQNQIRPLQLQAAGRGYANSTATPTPPASSPSRSS 776

  Fly   564 -VSVSLATAPPPLAPRRPSTLQLQASGAISASNSTLTTIHTTAPQAPAPTDFK------------ 615
             .|..|:|:..|...::  .|.|..:..|...:.|..|: |..|..|.||..|
  Fly   777 LESSDLSTSTSPSCGKK--ELMLLPTSVIRDDSVTTYTL-TLPPALPPPTRRKMNQTTQELAELA 838

  Fly   616 --------YYSPQRSTDSNLMRNYP-FPKAARGMRRQ---STMSVDSQKVNIAGY----QPLPMR 664
                    ....|.::.:| .|..| |....|..||:   .|.|.....::.:|.    .|.|:|
  Fly   839 ETLGFASNLQHSQHNSQTN-SRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLR 902

  Fly   665 KPYKHQEVMFELKSPTNRLT 684
              :.||.:.....:|...::
  Fly   903 --HHHQNLANSNSNPAKAMS 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	43/230 (19%)
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	27/82 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810