Protein Alignment app and Zdhhc4

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001013141.2
• Gene: Zdhhc4 / 304291
• RGDID: 1308389
• Length: 343
• Species: Rattus norvegicus
• Alignment Length: 320
• Identity: 87/320 - (27%)
• Similarity: 128/320 - (40%)
• Gaps: 103/320 - (32%)

  Fly    22 WELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFF 86
            :|:|:     ||..|..|.|        |:|:            |::..|:|         |.||
  Rat    85 YEVFS-----YCRELEFSLP--------CLLL------------PYVLLSVN---------LVFF 115

  Fly    87 TMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFT 151
            |:     |..|:||.|.:.:......:.:..||....||                      .|.|
  Rat   116 TL-----TCSTNPGTITKTNVSLLLQVYEFDEVMFPKNS----------------------RCST 153

  Fly   152 CKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVL 216
            |.:.:|.|:.||.:||.||.||||||.||.||:|..|..:|.::|::|...|..|...|...|:.
  Rat   154 CDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLLTLTASAATIAILSAAFLLR 218

  Fly   217 LMKKEHEVFNVIKA-------------APFTVIVVFICFFSIWSVIG--------LAG---FHTY 257
            |:    .|.|:.:.             ..|.:..:|:.|..|..::|        |||   |..|
  Rat   219 LV----AVSNLYQETYLDDLGRFQAVDTGFLIQHLFLAFPRIIFLLGFVIVLSLLLAGYLCFALY 279

  Fly   258 LTTSDQTTNEDLKG-----------SFSSKGGPRT-QNPYSRGNICLNCCHILCGPMTPS 305
            |..::|||||..:|           ::|....|:. ||.||.| :..|...:.. |.|||
  Rat   280 LAATNQTTNEWYRGDWAWCQHWPLVAWSPSAEPQIHQNIYSHG-LWSNLQEVFI-PATPS 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	49/147 (33%)
Zdhhc4	NP_001013141.2	Di-lysine motif. /evidence=ECO:0000250|UniProtKB:Q9NPG8	340..343