Protein Alignment app and Zdhhc25

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001034422.1
• Gene: Zdhhc25 / 300323
• RGDID: 1598341
• Length: 279
• Species: Rattus norvegicus
• Alignment Length: 310
• Identity: 85/310 - (27%)
• Similarity: 127/310 - (40%)
• Gaps: 103/310 - (33%)

  Fly    14 PNQRVTRKWELFAGRNKFYCD--GLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPA- 75
            ||||.   |        |..|  |:|            |.:  .|.||..:.....:.|.:.|:
  Rat    24 PNQRC---W--------FILDPIGIL------------CAM--ATWALVLSGGWVLVRDLLIPSN 63

  Fly    76 --IPIVGAVLYFFTMSSL-----LRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPR 133
              :.||...:.|..::||     |||..||||.:|..:                      ||.|.
  Rat    64 NMLYIVANGMIFHLLASLALVSHLRTMLTDPGSVPLGN----------------------RPGPD 106

  Fly   134 TKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVS 198
            |           :.||..|:...|.||:||::|..|:.:.|||||||.||||:.|.::|.||::.
  Rat   107 T-----------VSYCPDCRSAIPKRAAHCAVCKRCIRKNDHHCPWVNNCVGEDNQKYFLLFIMY 160

  Fly   199 LAFLAVFIFSCSVTHLVLLM---------KKEHE-VFNVIKAAPFT-VIVVFICFFSIWSVIGLA 252
            :..        |.||::||:         :.|.: ..:|...||.. :::|.:..|.:.||:...
  Rat   161 IGL--------SGTHVLLLLGIPVLCSYARGEWDSSSSVSPPAPILFLLLVALMGFVLSSVMLCT 217

  Fly   253 GFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRGNICLNCCHI--LCG 300
            ...|..|  |:||.|.|           .||.:|.||.. .|.::  :||
  Rat   218 QMCTIYT--DKTTTELL-----------YQNTHSPGNRA-KCANLKAICG 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	44/134 (33%)
Zdhhc25	NP_001034422.1	DHHC	110..230	CDD:396215	43/129 (33%)