Protein Alignment app and ZDHHC1

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Alignment Length: 149
• Identity: 48/149 - (32%)
• Similarity: 65/149 - (43%)
• Gaps: 32/149 - (21%)

  Fly   148 YCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVT 212
            :|..|.:....|:.|||.|:.||..|||||.|:.||||:||||.| |..|:.|.|.|.:.....|
Human   135 HCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLF-LHSVASALLGVLLLVLVAT 198

  Fly   213 HLVL--------LMKKEHEVFNVIK-----------AAPF-TVIVVFICFFSIWSVIGLAG---- 253
            ::.:        |....|  |.|:|           |||. |.....:...::..::||..
Human   199 YVFVEFFVNPMRLRTNRH--FEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALL 261

  Fly   254 -----FHTYLTTSDQTTNE 267
                 ||.||.....||.|
Human   262 GHLLCFHIYLMWHKLTTYE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	48/149 (32%)
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		43/138 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		DHHC	129..284	CDD:396215	48/149 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485