Protein Alignment app and Zdhhc19

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001034348.1
• Gene: Zdhhc19 / 288045
• RGDID: 1309014
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 341
• Identity: 93/341 - (27%)
• Similarity: 143/341 - (41%)
• Gaps: 83/341 - (24%)

  Fly    52 LITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQ 116
            |:...|.|||.|.|.:|..:.....|.|...|:..|..||:...|:|||::.|.|..|
  Rat    40 LLVFLSGLFFGFPCRWLVQNGEWVFPAVTGPLFILTFFSLVSLNFSDPGILHRGSVSE------- 97

  Fly   117 IEVPNSLNSPTYRPPPRTKEVL-VKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWV 180
                          .|||..|: |..:..:|::|..|...||||..||..|:.||:.|||||.||
  Rat    98 --------------DPRTVHVVRVNQRAFRLEWCPKCLFHRPPRTYHCPWCNICVEDFDHHCKWV 148

  Fly   181 GNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIV----VFIC 241
            .||:|.||:|.|.|.::   ||.::..:..||.|:.|:...|..|::.||....|.|    ..|.
  Rat   149 NNCIGHRNFRLFVLLIL---FLCLYSGALLVTCLMFLIHTSHLPFSLDKAMAILVAVPAAGFLIP 210

  Fly   242 FFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQ-NPYSRGNICLNCCHILCGPMTPS 305
            .|.:..:..|:     ::.:::        |:.||.....: ||:.:| ...|....:|.|:.|:
  Rat   211 LFLLMLIQALS-----VSRAER--------SYESKCRDHEEYNPFDQG-FAKNWYLTMCAPLGPN 261

  Fly   306 LID-----RRGIATDEFIQQMQH----------------QSSPRH-------------ALSDVLS 336
            .:.     :|.:.|:...::.:|                |..|||             ||.::.|
  Rat   262 YMSEVVCLQRPVGTERIQEKTKHPPPCPPKPCGPGHPGPQIQPRHTRGKGPPGSGEAAALQEMRS 326

  Fly   337 ASHMVTTS-----QPM 347
            ....|..|     |||
  Rat   327 LPASVEKSPGGPRQPM 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	42/127 (33%)
Zdhhc19	NP_001034348.1	DHHC	112..230	CDD:396215	43/133 (32%)