Protein Alignment app and ZDHHC22

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001351101.1
• Gene: ZDHHC22 / 283576
• HGNCID: 20106
• Length: 263
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 62/254 - (24%)
• Similarity: 99/254 - (38%)
• Gaps: 74/254 - (29%)

  Fly    47 YLTCI-LITGTSALFFAF----DCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRAS 106
            |..|| |:|....||...    :.|..|...:||: :.||:..|.:.::|.....    ||..:.
Human    14 YFLCISLVTFVLQLFLFLPSMREDPAAARLFSPAL-LHGALFLFLSANALGNYVL----VIQNSP 73

  Fly   107 NDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASH-CSLCDNCV 170
            :|..|                           .:|.:.:...|       |..::| |.:|....
Human    74 DDLGA---------------------------CQGASARKTPC-------PSPSTHFCRVCARVT 104

  Fly   171 DRFDHHCPWVGNCVGKRNYRFFYLF------------LVSLAFLAVFIFSCSVTH----LVLLMK 219
            .|.||||.:.|||:|.||.|.|.||            :..:|:::. :.|.|..|    |.||..
Human   105 LRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISA-VLSISFAHPLAFLTLLPT 168

  Fly   220 KEHEVFN--VIKAAPFTVIVVFICFFSIWSVIGL--AGF---HTYLTTSDQTTNEDLKG 271
            ...:.|:  |:.:..|.:::::     :|..|||  |||   ...|....||.::..||
Human   169 SISQFFSGAVLGSEMFVILMLY-----LWFAIGLACAGFCCHQLLLILRGQTRHQVRKG 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	40/147 (27%)
ZDHHC22	NP_001351101.1	DHHC	92..218	CDD:366691	38/131 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810