DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment app and AT2G14255

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_973453.2	Gene:	AT2G14255 / 2745525	AraportID:	AT2G14255	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	125/284 - (44%)	Gaps:	35/284 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAI-PIVGAVLYF------F 86
            :|.:|..|..::....:|.|..||:.       .|....::.|..|.| .:||....|      :
plant   258 DKIFCGKLGETSYAPMLFSLIVILMV-------LFITSIVSASNLPKITAMVGLWACFGLSCGVY 315

  Fly    87 TMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFT 151
            .:.:..|.:..|||.:.|.....:.:......:..:..:|::           ||...:|  |.|
plant   316 ALITFYRVSRKDPGYVKRTGEANSQHTANDPLIDINFKNPSW-----------KGNWSQL--CPT 367

  Fly   152 CKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVL 216
            |||.||.|:.||..|..||::|||||||:.|||||:|.|:|.:|::..|..:....:.:|..|..
plant   368 CKIIRPVRSKHCPTCKRCVEQFDHHCPWISNCVGKKNKRYFLVFVIMGALTSFVGGTTAVQRLWR 432

  Fly   217 LMKKEHE----VFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGS-FSSK 276
            .:.:.|.    :.:::...|...:.:|.......:.:.|....:|:...:.||||..... ||..
plant   433 GIPQVHHGESWIKHIVIEHPDAAVFLFFDLLIFIATMTLTISQSYMIARNITTNELWNAKRFSYL 497

  Fly   277 GGP--RTQNPYSRGNICLNCCHIL 298
            .||  |..|||:.| :..||...|
plant   498 RGPDGRFYNPYNHG-LRRNCTDFL 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	42/127 (33%)
AT2G14255	NP_973453.2	Ank_4	28..78	CDD:290365
		ANK repeat	57..88	CDD:293786
		ANK	57..85	CDD:197603
		Ank_2	62..188	CDD:289560
		ANK	85..211	CDD:238125
		ANK repeat	92..155	CDD:293786
		Ank_5	110..165	CDD:290568
		ANK repeat	157..188	CDD:293786
		Ank_5	176..233	CDD:290568
		ANK repeat	190..214	CDD:293786
		ANK repeat	225..254	CDD:293786
		zf-DHHC	363..492	CDD:279823	42/130 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910