Protein Alignment app and Zdhhc22

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001074412.1
• Gene: Zdhhc22 / 238331
• MGIID: 2685108
• Length: 263
• Species: Mus musculus
• Alignment Length: 265
• Identity: 60/265 - (22%)
• Similarity: 101/265 - (38%)
• Gaps: 73/265 - (27%)

  Fly    47 YLTCI-LITGTSALFFAF----DCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRAS 106
            |..|| |:|....||...    :.|......:||: :.||:..|.:.::|
Mouse    14 YFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAV-LHGALFLFLSANAL--------------- 62

  Fly   107 NDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASH-CSLCDNCV 170
               ..|:......|:.|.:             .:|...:...|       ||.::| |.:|....
Mouse    63 ---GNYVLVIQNSPDDLGT-------------CQGTMSQRPQC-------PPPSTHFCRVCSRVT 104

  Fly   171 DRFDHHCPWVGNCVGKRNYRFFYLF------------LVSLAFLAVFIFSCSVTH----LVLLMK 219
            .|.||||.:.|||:|.||.|.|.||            :..:|:::. :.|.|..|    |.||..
Mouse   105 LRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISA-VLSISFAHPLAFLTLLPT 168

  Fly   220 KEHEVFN--VIKAAPFTVIVVFICFFSIWSVIGL--AGF--HTYLTTSDQTTNEDLKGSFSSKGG 278
            ...:.|:  |:.:..|.:::::     :|..:||  |||  |..|......|...::...:.:..
Mouse   169 SISQFFSGAVLGSDMFVILMLY-----LWFAVGLACAGFCCHQLLLILRGQTRYQVRKGMAVRAR 228

  Fly   279 PRTQN 283
            |..:|
Mouse   229 PWRKN 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	40/146 (27%)
Zdhhc22	NP_001074412.1	DHHC	91..218	CDD:366691	38/132 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810