Protein Alignment app and Zdhhc14

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_666185.3
• Gene: Zdhhc14 / 224454
• MGIID: 2653229
• Length: 489
• Species: Mus musculus
• Alignment Length: 516
• Identity: 232/516 - (44%)
• Similarity: 296/516 - (57%)
• Gaps: 115/516 - (22%)

  Fly    20 RKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLY 84
            ||||:|.|||||:|:|.:|.|..|||||||.|||..||.|||||||.:||:.|.||||:||.:|:
Mouse    38 RKWEVFPGRNKFFCNGRIMMARQTGVFYLTLILILVTSGLFFAFDCRYLAEKITPAIPVVGGILF 102

  Fly    85 FFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYC 149
            ||.|.:||||:|:||||:|||:.||||.:|:||::.|..:|..||||||||||::.|||||||||
Mouse   103 FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVVINGQTVKLKYC 167

  Fly   150 FTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHL 214
            |||||||||||||||||||||::|||||||||||||||||||||:|::||:||.||||:..:||
Mouse   168 FTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITH- 231

  Fly   215 VLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGP 279
            |:...::....:.:|.:|.:|:...|||||:||:|||:||||||.:|:||||||:|||:|:|.|.
Mouse   232 VIHRSQQKGFLDALKDSPASVLEAVICFFSVWSIIGLSGFHTYLISSNQTTNEDIKGSWSNKRGK 296

  Fly   280 RTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTS 344
            ...||||.|||..|||..||||::||||||||     ::|.                     .|.
Mouse   297 ENYNPYSYGNIFTNCCVALCGPISPSLIDRRG-----YVQP---------------------DTP 335

  Fly   345 QPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFDHPPPS 409
            ||          .....||::.||
Mouse   336 QP----------AAPSNGITMYGA----------------------------------------- 349

  Fly   410 YDLVQNGKSRKHHQQRC--SLQTLLPASAQQQFKASKHKHKQLKQHLVAAELQQHEGGPGPG--- 469
                ...:|....|.:|  |.:.:|.|:|....        |.:..|.:.||.. .|.||.|
Mouse   350 ----TQSQSDMCDQDQCIQSTKFVLQAAATPLL--------QSEPSLTSEELHM-PGKPGLGTPC 401

  Fly   470 -------PNSPSLLRSPATSSSYR----LNLKRSLHLPLTPSYDDVRHSP------LPLLH 513
                   |..||.:.:.||.::..    |..:...|..|||  |:....|      .||.|
Mouse   402 ASLTLGQPTPPSSMPNLATEATLSDIMPLKDEHGGHQFLTP--DEAPSPPRMLGAGSPLAH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	84/123 (68%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	85/125 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	434..454		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841751
Domainoid	1	1.000	201	1.000	Domainoid score	I3001
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62301
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm44215
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	LDO	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R405
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740