Protein Alignment app and dhhc-11

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_491675.3
• Gene: dhhc-11 / 188748
• WormBaseID: WBGene00020694
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 82/359 - (22%)
• Similarity: 138/359 - (38%)
• Gaps: 78/359 - (21%)

  Fly    46 FYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEA 110
            :.|:.|:|..|..:.:    |.|......|||::..::|.    .::..|..:|     ||::
 Worm    20 YILSIIMIPATMYVVY----PILPSYFWIAIPVLYGLIYI----QVIYMTIYEP-----ASSE-- 69

  Fly   111 AYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDH 175
              ::::::..:.:..|......|        ..:...:|..|::.......||..|:.|:|.|||
 Worm    70 --LKEKVKSEHFVRKPYESEAGR--------HVITNSFCSICEVRTYRETKHCKRCNFCIDDFDH 124

  Fly   176 HCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLV--LLMKKEHEVFNVIKAAPFTVIV- 237
            ||.|:.||:|.:|||.|.:.::.:...::|.|..||....  :....|..:..:::...|..|.
 Worm   125 HCVWLNNCIGGKNYRPFVVLVICVNVFSMFCFGLSVVIFFSWITNSDERALIKLVQDKDFLKISW 189

  Fly   238 VFICFFS--IWSVIG-----LAGFHTYLTTSDQTTNEDLKGS-FSSKGGPRTQNPYSRGNICLNC 294
            ||:|...  |:.|:.     |..||..|....|||...:... .|:|.|.              .
 Worm   190 VFLCVICIIIYGVLSVTTAHLLYFHFKLFKVGQTTYRYMTNQRRSAKVGA--------------I 240

  Fly   295 CHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASH-----MVTTSQPMMGGLGGG 354
            .|:  .| |.|...||....:|.: ||....:|  .||.:|...:     .||...|..
 Worm   241 SHV--SP-THSQTHRRDGDIEEGV-QMDEMGNP--PLSPILEDDYDGQRITVTVEAPTP------ 293

  Fly   355 GIGGAGGGISIGGAELKPRFYDESNPSSSTLEGN 388
                     :..|:.:....|  |||.....|||
 Worm   294 ---------TPNGSTVSTASY--SNPGYVVNEGN 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	39/133 (29%)
dhhc-11	NP_491675.3	DUF485	14..75	CDD:294756	14/71 (20%)
		zf-DHHC	91..231	CDD:279823	39/139 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810