Protein Alignment app and dhhc-2

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_493007.2
• Gene: dhhc-2 / 173062
• WormBaseID: WBGene00012948
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 137/323 - (42%)
• Similarity: 195/323 - (60%)
• Gaps: 31/323 - (9%)

  Fly    12 MAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAI 76
            :.|:....|||:...|||:|.|.|.|:.:...|.|.:|.||:..|..::|.||.|||. ..:|||
 Worm    67 LPPSDPKRRKWQSHPGRNRFGCGGRLVCSRSHGAFVVTVILMIATLTVYFVFDAPFLW-GYSPAI 130

  Fly    77 PIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKG 141
            |||.|||....:::...|:|||||::||..|.|...:::|....|.:|...:. .||.::|:|.|
 Worm   131 PIVAAVLSLIVITNFFATSFTDPGILPRVDNIEIIEMDRQQANGNGINDVAHL-RPRFQDVVVNG 194

  Fly   142 QTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFI 206
            :.||:|||.||:::||||.|||::|||||..|||||||||||:|.|||.:||.|:..|:.|.:::
 Worm   195 EHVKMKYCTTCRLYRPPRCSHCAICDNCVLMFDHHCPWVGNCIGLRNYTYFYRFVFCLSILVIYL 259

  Fly   207 FSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKG 271
            |:.:|||:.|| .:|....:|::..|.:.:|:.||||:.||:||||.|||||..:|.||||||||
 Worm   260 FASAVTHISLL-AQEMPFGDVMRKTPGSAVVIVICFFTTWSIIGLACFHTYLLCADLTTNEDLKG 323

  Fly   272 SF-------------------SSKGGPRTQNPYSRGNICLNCCHILCGPM----TPSLIDRRG 311
            .:                   :|..|..|:||:..|     |.....|.:    .|||:|.||
 Worm   324 LYRRKHRPTPPSSTPSTSAATNSSVGHSTKNPFYAG-----CFKSFFGRLFKSRFPSLLDARG 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	68/123 (55%)
dhhc-2	NP_493007.2	DHHC	72..>319	CDD:418707	116/249 (47%)