Protein Alignment app and ZDHHC19

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001034706.1
• Gene: ZDHHC19 / 131540
• HGNCID: 20713
• Length: 309
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 84/296 - (28%)
• Similarity: 130/296 - (43%)
• Gaps: 59/296 - (19%)

  Fly    14 PNQRVTRKW---ELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPA 75
            |...|.|.|   .|||..|                    .:|:...|.|||||.|.:||.:...|
Human    16 PLPLVPRPWFLPSLFAAFN--------------------VVLLVFFSGLFFAFPCRWLAQNGEWA 60

  Fly    76 IPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVL-V 139
            .|::...|:..|..||:...|:|||::.:.|.::.                     |.|..|: |
Human    61 FPVITGSLFVLTFFSLVSLNFSDPGILHQGSAEQG---------------------PLTVHVVWV 104

  Fly   140 KGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAV 204
            .....:|::|..|...||||..||..|:.||:.|||||.||.||:|.||:|||.|.::|   |.:
Human   105 NHGAFRLQWCPKCCFHRPPRTYHCPWCNICVEDFDHHCKWVNNCIGHRNFRFFMLLVLS---LCL 166

  Fly   205 FIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDL 269
            :..:..||.|:.|::..|..|:..||     |.:.:...:...::.|:........|..:.:...
Human   167 YSGAMLVTCLIFLVRTTHLPFSTDKA-----IAIVVAVSAAGLLVPLSLLLLIQALSVSSADRTY 226

  Fly   270 KGSFSSKGGPRTQNPYSRGNICLNCCHI-LCGPMTP 304
            ||......|   .||:.:|  |.:..:: :|.|:.|
Human   227 KGKCRHLQG---YNPFDQG--CASNWYLTICAPLGP 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	41/123 (33%)
ZDHHC19	NP_001034706.1	DHHC	109..>181	CDD:396215	34/74 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..309