Protein Alignment app and app

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_061498731.1
• Gene: app / 1274788
• VectorBaseID: AGAMI1_013767
• Length: 858
• Species: Anopheles gambiae
• Alignment Length: 788
• Identity: 337/788 - (42%)
• Similarity: 430/788 - (54%)
• Gaps: 180/788 - (22%)

  Fly    12 MAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAI 76
            |||:|:||:|||:|||||||:|||.||:||::||||.|.||||.||.|||.|||||||..|.|||
Mosquito     1 MAPSQKVTKKWEIFAGRNKFFCDGYLMTAPNSGVFYFTVILITATSGLFFVFDCPFLAQRITPAI 65

  Fly    77 PIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKG 141
            ||:|.:|:.||:|||.||.|:|||:|||||.||||||||||||||||||||||||||||||.|||
Mosquito    66 PIIGGILFVFTLSSLFRTAFSDPGIIPRASQDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVFVKG 130

  Fly   142 QTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFI 206
            ||||||||||||||||||||||||||||||||||||||||||||||||||||:|:||||||||||
Mosquito   131 QTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYMFIVSLAFLAVFI 195

  Fly   207 FSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKG 271
            |||:.||:|:|:|::::..:|:|..|.:||:..|||.|:|||||||||||||||||||||||:||
Mosquito   196 FSCTTTHIVMLLKEDNQFIDVVKRTPSSVIIAIICFCSVWSVIGLAGFHTYLTTSDQTTNEDIKG 260

  Fly   272 SFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHAL----- 331
            |||||||.:..||||:|||||||.||||||:|||||||||:.|||:..|||.......|.
Mosquito   261 SFSSKGGQQAINPYSQGNICLNCFHILCGPITPSLIDRRGVVTDEYRTQMQATEKYNSATVPPLV 325

  Fly   332 -----SDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYD--------------- 376
                 .|.|:..:  :....:.....|||:||.|        ..:.|.||
Mosquito   326 VMQPGMDTLNKHY--SMEHELQNASNGGGVGGTG--------VYRQRSYDNLQNVPIPTNFKYFA 380

  Fly   377 -ESNPSSSTLEGNGGAINGH-----------GNGHGNGFDHPPPSYDLVQNG---------KSRK 420
             :|..|:|.:....||..|.           |:..|.|..   ||..|::.|         ||:.
Mosquito   381 PQSKYSASGVSIANGAAGGGAYCYSDQSQLLGSSLGGGIS---PSTVLLRGGGGTGTMPLLKSQS 442

  Fly   421 ---HHQQRCSLQTLLPASAQQQFKASKHKHKQLKQHLVAAELQQHEGGPGPGPNSPSLLRSPATS 482
               |:.|......|.|::..          ...:|||:..:...|                |..:
Mosquito   443 EFLHNTQHQPQHPLTPSAGT----------SVSQQHLLQQQKAAH----------------PLHT 481

  Fly   483 SSYRLNL-----KRSLHLPLTPSYDDVRHSPLPLLHHH--VHAQQTTAIGTVAAAAAA------- 533
            .|..:.|     .|:..:.:..|..|::   ||:..||  ...:||..:.....|.:|
Mosquito   482 MSLNMTLPRYPYHRNRAIGIRKSSHDLQ---LPIYQHHPLEDGKQTNGLAHGGGAYSAGLYCLGN 543

  Fly   534 VASGASGTN------------------------------TGTGTGTGGSSSSATTTAPTSVSVSL 568
            :..|.:.||                              :.:.:.:|||||||:.:..|..|.|.
Mosquito   544 LGPGGNSTNSLNNHFNPAAAPGAAPIVIPYSNGLMLKNSSASSSSSGGSSSSASASTATISSNST 608

  Fly   569 ATAPPPLAPRRPSTLQLQASGAIS--ASNSTLTTIHTTAPQ-----AP-----APTDFKYYSPQR 621
            ::|...|..|..|.|....||:.|  ||..|:||:.....|     ||     :|...:..||..
Mosquito   609 SSATSSLDRRCRSNLLPSGSGSGSYLASYDTITTLSDQQQQQRQNVAPHTCPNSPRTIRCGSPSC 673

  Fly   622 STDSNLMRNYPFPKAARGMRRQSTMSVDSQKVNIAGYQPLPMRKPYKHQEVMFELKSPTNRLTIR 686
            |::.:.|.:   .|.:.|.::..:          .||.      .::|.:              :
Mosquito   674 SSELDPMLH---SKGSGGGKQHGS----------GGYH------RHRHHQ--------------Q 705

  Fly   687 ECDFGGGG 694
            :...||||
Mosquito   706 QAAGGGGG 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	99/123 (80%)
app	XP_061498731.1	None