DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment app and si:ch211-223a10.1

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	XP_009305694.1	Gene:	si:ch211-223a10.1 / 101884554	ZFINID:	ZDB-GENE-090313-86	Length:	544	Species:	Danio rerio

Alignment Length:	167	Identity:	43/167 - (25%)
Similarity:	77/167 - (46%)	Gaps:	17/167 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 EVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLA 200
            :::..||:.. ::|..|::.:.....||.|||.|:..:||||.::..|||:.|:|.|.|||:|:.
Zfish   376 DLMEAGQSPD-RFCIYCELIQVENCKHCRLCDMCIKDYDHHCLFINQCVGRENHRTFILFLMSMV 439

  Fly   201 FLAVFIFSCSVTHLVLLMK--KEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQ 263
            ...:.....::.:|.|.:.  :..:..:|.....:.:::..:...|::.|..|.|......:...
Zfish   440 MAHLIFILSAIFYLYLKVSGLQLSDWGSVAGREAWVLLLTLLNLLSLFWVGWLLGEQLDAISRGT 504

  Fly   264 TT---NEDLKG-----------SFSSKGGPRTQNPYS 286
            ||   ..||||           ||..:|..|.|...|
Zfish   505 TTYYRRYDLKGPSKRQRLGTVVSFLLEGKRRQQRSQS 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	32/128 (25%)
si:ch211-223a10.1	XP_009305694.1	ANK repeat	7..36	CDD:293786
		Ank_2	9..102	CDD:289560
		ANK	39..159	CDD:238125
		ANK repeat	39..69	CDD:293786
		ANK repeat	71..102	CDD:293786
		Ank_2	76..162	CDD:289560
		ANK repeat	138..170	CDD:293786
		Ank_4	139..192	CDD:290365
		zf-DHHC	384..509	CDD:279823	31/125 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810