Protein Alignment app and zdhhc14

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_004914695.1
• Gene: zdhhc14 / 100489334
• XenbaseID: XB-GENE-998053
• Length: 481
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 243/499 - (48%)
• Similarity: 304/499 - (60%)
• Gaps: 64/499 - (12%)

  Fly    18 VTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAV 82
            |.||||:|.|||||||||.:|.|..|||||||.|||..||.||||||||:||..|.||||::|.:
 Frog    28 VRRKWEVFPGRNKFYCDGRVMMARQTGVFYLTLILILVTSGLFFAFDCPYLAVKITPAIPVIGGI 92

  Fly    83 LYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLK 147
            |.||.|.:||||:|:||||:|||:.||||.:|:||:|.|...|..||||||||||::.|||||||
 Frog    93 LVFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDVANGSTSGGYRPPPRTKEVVINGQTVKLK 157

  Fly   148 YCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVT 212
            |||||||||||||||||||||||:||||||||||||||||||||||:|::||:||.||||:..:|
 Frog   158 YCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVIT 222

  Fly   213 HLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKG 277
            | |:|..::....|.:|.:|.:|:...:||||:||::||:||||||.:|:||||||:|||:|||.
 Frog   223 H-VILRSQQSGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSSKR 286

  Fly   278 GPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALS---DVLSASH 339
            |....||||.|||..|||..||||:.||||||||....:..|.:    ||.:.|:   ...|.|:
 Frog   287 GKENYNPYSYGNIFKNCCAALCGPVNPSLIDRRGFVPADMPQAV----SPSNGLTMYGSTQSQSN 347

  Fly   340 MVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFD 404
            |....|.:....            .:..|...|...:|.:.:|..|. ..|..:.|.........
 Frog   348 MCDQDQCIQSTK------------FVLQAAATPLLQNEPSVTSDELP-LPGKTSIHAPCTSLALG 399

  Fly   405 HP-PPSYDLVQNGKSRKHHQQRCSLQTLLPASAQQQFKASKHKHKQLKQHLVAAELQQHEG-GPG 467
            .| |||        |..:......|..::|                ||:     :|..|:. .|.
 Frog   400 QPTPPS--------SMPNLNSESILTDMIP----------------LKE-----DLGNHQFLTPD 435

  Fly   468 PGPNSPSLL--RSPATSS--SYRLNL--KRSLHLPLTPSYDDVR 505
            ..|:.|.:|  .||.|.|  .:.|||  :.|||      .|.||
 Frog   436 EAPSPPGMLPVNSPVTHSHTMHVLNLVSQDSLH------EDSVR 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	85/123 (69%)
zdhhc14	XP_004914695.1	DHHC	156..279	CDD:396215	85/123 (69%)