DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment app and zdhhc20b

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	XP_005162815.2	Gene:	zdhhc20b / 100001188	ZFINID:	ZDB-GENE-091117-30	Length:	409	Species:	Danio rerio

Alignment Length:	227	Identity:	68/227 - (29%)
Similarity:	103/227 - (45%)	Gaps:	48/227 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 SLLRTTFTDPG------VIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTV---- 144
            |..:|.||.|.      .:|::..::   .||:            :.|...:|:|.|..|.
Zfish    97 SYWKTIFTKPANPSKEFCLPKSEKEQ---YEKE------------QRPETQQEILKKVATSLPLY 146

  Fly   145 ------KLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLF----LVSL 199
                  .::||..|::.:|.|..|||.||.||.:.|||||||.||||..||:||.||    ||..
Zfish   147 TRTGAGAIRYCDRCQVIKPDRCHHCSACDMCVLKMDHHCPWVNNCVGFSNYKFFILFLTYSLVYC 211

  Fly   200 AFLAVFIFSCSVTHLVLLMKKEHEVFNVIKA------APFTVIVVFI--CFFSIWSVIGLAGFHT 256
            .|:|..:....:....|..:|..|  |..|:      |.|.|:.:|.  ..|.| |::.|..:|.
Zfish   212 LFIAASVLQYFIKFWTLCRRKSAE--NCPKSDLPESHAKFHVLFLFFVAAMFCI-SILSLFTYHL 273

  Fly   257 YLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRG 288
            :|...:::|.|..:... .:.|| .:|.:|.|
Zfish   274 WLVGKNRSTIEAFRAPV-FRNGP-DKNGFSLG 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	50/135 (37%)
zdhhc20b	XP_005162815.2	zf-DHHC	44..342	CDD:327686	68/227 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910