DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adk1 and Ak7

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_084463.1	Gene:	Ak7 / 78801	MGIID:	1926051	Length:	723	Species:	Mus musculus

Alignment Length:	182	Identity:	32/182 - (17%)
Similarity:	75/182 - (41%)	Gaps:	50/182 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EELRRARAAADIPI-IWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVA------------ 72
            :|.:::|..  :|| |.|||.|..||.:...::.:.|...|:...|::...:|
Mouse   357 KEYKQSRGL--LPIKICILGPPAVGKSSISEELAKYYKLHHIKMKDVIAEAIAKLEAIVAPKDSV 419

  Fly    73 SGSDKGRQ-----------------LQAVMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYP 120
            .|.::|.:                 .:::..:.|.:.:..::..:.:.:......::||::||:|
Mouse   420 EGEEEGEEEEEEENVDDAQELLDGIKESMEQNAGRLEDQYIIRFVKEKLKSMPCRNQGFILDGFP 484

  Fly   121 R------------QKNQGIEFEARIAPAD--LALYFEC----SEDTMVQRIM 154
            :            ::.:..|...:|.|.|  :...|.|    |::.:.:|:|
Mouse   485 KTYDQAKDLFNQEEEEEEEEIRGKIFPYDKLITPEFVCGLDASDEFLKERVM 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	30/173 (17%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	29/169 (17%)
Ak7	NP_084463.1	WcaG	<147..297	CDD:223528
		NADB_Rossmann	<218..298	CDD:304358
		ADK	369..>548	CDD:238713	28/168 (17%)
		Dpy-30	679..720	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900