DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and Ak9

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001357742.1	Gene:	Ak9 / 633979	MGIID:	2685080	Length:	1879	Species:	Mus musculus

Alignment Length:	191	Identity:	49/191 - (25%)
Similarity:	88/191 - (46%)	Gaps:	14/191 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KEAEEKL---KAEELRRARAAADIPI-IWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVA 72
            |:.:||.   ..:.:|:.:..|.:|: |.|:|.|..||.|...|:...||...||.||.||..:.
Mouse  1355 KQTKEKFMMNPIKYIRQPKPKATMPVRIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLN 1419

  Fly    73 S--GSDKGRQLQAVMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFEAR-IA 134
            :  .|:....|...:..|..|.::..:..|:.::..:..::.|.:|||||...:|....||| |.
Mouse  1420 NHPDSELSLMLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLEARSII 1484

  Fly   135 PADLALYFEC---SEDTMVQRIMARAAASAVKRDDDNEKTIRA-RLLTFKQNTNAILELYE 191
            |   .:.||.   |::...:.::.:....::.....|...|.| :...:.:|.|.|.:.|:
Mouse  1485 P---MVIFELHVPSKEIFKRLLLEKKTEQSMSYPLHNSSQIIAYKNAKYHKNINEIRQFYQ 1542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	45/170 (26%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	43/166 (26%)
Ak9	NP_001357742.1	adk	34..286	CDD:273569
		Ribosomal_L24e_L24	<926..956	CDD:382277
		ADK	962..1177	CDD:238713
		ADK	1381..1553	CDD:238713	43/165 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900