DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adk1 and ak9

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_685909.5	Gene:	ak9 / 557708	ZFINID:	ZDB-GENE-041014-337	Length:	1762	Species:	Danio rerio

Alignment Length:	226	Identity:	57/226 - (25%)
Similarity:	100/226 - (44%)	Gaps:	28/226 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LRRARAAADIPI-IWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLR---NEVASGSDKGRQLQA 83
            ||:.|....:|| :.|:|.|..||.|.......:||.|.||.||.:|   |..|. :|...|:|.
Zfish  1246 LRQPRPNPSLPIKLAIIGPPKSGKTTVAQAFAREYGLTRLSIGDAIRMVLNSQAK-TDLACQVQI 1309

  Fly    84 VMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDT 148
            .:..|..|.::..:..:..|:.....:::||::||:|..|:|....|:.|.|   .:..|...||
Zfish  1310 HLKQGQTVPDELAIQCVEVAVMNLVCTTRGFVLDGFPVTKHQAELLESCIIP---MVVVELQLDT 1371

  Fly   149 MVQRIMARAAASAVKRD------DDNEKTIRARLLTFKQNTNAI-LELYEP----------KTLT 196
            :  .::.|......|.:      .|:.:.:..|...|:|...|: |.|:..          |:..
Zfish  1372 V--EVLKRGLRDREKNNRSHQVHHDSLQALNIRNSCFRQEAEALRLHLHNQYHNWTPVDAHKSKW 1434

  Fly   197 INAERDVDDIFLEVVQAIDCVLKKKQQNAAA 227
            ...||.:|::.:. ::.|...|::..:..||
Zfish  1435 WVQERILDEVRIS-MRHIHSYLERIHKGQAA 1464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	51/207 (25%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	49/192 (26%)
ak9	XP_685909.5	adk	33..280	CDD:273569
		ADK	33..276	CDD:238713
		AAA_17	394..504	CDD:289950
		DUF3508	<717..804	CDD:288841
		Ribosomal_L24e_L24	<775..808	CDD:294589
		NK	816..>983	CDD:302627
		Adk	1258..1445	CDD:223637	48/192 (25%)
		ADK	1258..1432	CDD:238713	44/179 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810