DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and ak7b

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001103168.2	Gene:	ak7b / 504040	ZFINID:	ZDB-GENE-050309-170	Length:	699	Species:	Danio rerio

Alignment Length:	246	Identity:	53/246 - (21%)
Similarity:	97/246 - (39%)	Gaps:	51/246 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EELRRARAAADIPI-IWILGGPGCGKGTQCAKIVEKYGFTHL----SSGDLLRN--------EVA 72
            ||.:.:|..  :|| :.|:|.|..||.|...||.:.|...|:    :..:.|.|        :..
Zfish   351 EEYKESRGL--LPIRMCIVGPPAVGKSTIAEKICKHYNLHHIKLKEAIAEALENLELCVRTEDEE 413

  Fly    73 SGSDKGRQL-----QAVMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIE-FEA 131
            :..|..::.     :.:..:||.:.:..|:.::.|.:......::||::||:|:...|..| |..
Zfish   414 NDQDDDQEFWDTLRENMNENGGRLDDQYVIRIMKDKLRTKPCMNQGFVLDGFPKTCEQAKELFTG 478

  Fly   132 RIAPADL------------ALYFECSEDTMVQRIMARAAASAVKRDDDNEKTIRARLLTFKQ--- 181
            ...|.||            ......::|.:..|:: ....:.|:......:....||..|:.
Zfish   479 DGEPEDLESKHATKIIPEFVFSVNATDDFLKNRVL-NLPETVVEGTSYMPEQFLQRLARFRDRNV 542

  Fly   182 ------NTNAILELYEPKTLTINAERDVDDIFLEVVQAIDCVLKK--KQQN 224
                  |....||:: |:.|.|.::.|     .|....||.:.||  |.:|
Zfish   543 EDEMPLNYFEDLEIH-PEHLEITSDND-----NEYQLIIDKICKKVGKPRN 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	46/226 (20%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	42/211 (20%)
ak7b	NP_001103168.2	WcaG	<129..>286	CDD:223528
		NADB_Rossmann	<212..286	CDD:304358
		Adk	363..583	CDD:223637	46/226 (20%)
		ADK	363..556	CDD:238713	36/193 (19%)
		Dpy-30	656..697	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900