DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Adk1 and Ak4

DIOPT Version :9

Sequence 1:NP_729792.1 Gene:Adk1 / 39396 FlyBaseID:FBgn0022709 Length:229 Species:Drosophila melanogaster
Sequence 2:NP_058831.1 Gene:Ak4 / 29223 RGDID:2078 Length:223 Species:Rattus norvegicus


Alignment Length:186 Identity:53/186 - (28%)
Similarity:89/186 - (47%) Gaps:36/186 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 ILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVMASGGLVSNDEVLS--L 99
            |||.||.||||.|.:|.:.:|..|||||.|||..:.:.::.|...:..:..|.||. |.|::  :
  Rat    10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTNTEVGDVAKQYLEKGLLVP-DHVITRLM 73

  Fly   100 LNDAITRAKGSSKGFLIDGYPRQKNQGIEFEA--RIAPADLALYFECSEDTMVQRIMAR------ 156
            :::..||   |::.:|:||:||..   ::.||  ||...||.:......:|:..|:..|      
  Rat    74 MSELETR---SAQHWLLDGFPRTL---VQAEALDRICDVDLVISLNIPFETLKDRLSRRWIHPSS 132

  Fly   157 -------------------AAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPK 193
                               .....|:::||..:.:.|||..:|.....::|||:.:
  Rat   133 GRVYNLDFNPPQVLGVDDITGEPLVQQEDDKPEALAARLRRYKDAAKPVIELYKSR 188

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Adk1NP_729792.1 aden_kin_iso1 30..217 CDD:130427 53/186 (28%)
ADK 34..206 CDD:238713 53/186 (28%)
Ak4NP_058831.1 adk 7..211 CDD:273569 53/186 (28%)
NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03170 35..64 8/28 (29%)
LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03170 125..162 2/36 (6%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0563
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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