DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and Ak5

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_011238417.1	Gene:	Ak5 / 229949	MGIID:	2677491	Length:	566	Species:	Mus musculus

Alignment Length:	174	Identity:	77/174 - (44%)
Similarity:	114/174 - (65%)	Gaps:	8/174 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EELRRARAAADIPIIWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVM 85
            |:||:.:      ||:::||||.||||||.|:.|||||||||:|:|||.|:.|.|::.:.::.:|
Mouse   371 EDLRKCK------IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIM 429

  Fly    86 ASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMV 150
            ..|.||.:..||.||.:|:..:.|::||||||||||:..||.||..||....|.:..:||.|||.
Mouse   430 ERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMT 494

  Fly   151 QRIMARAAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPKT 194
            .|::.|:.:|  :|.:|..|:|..||..:.:.:..::..||.||
Mouse   495 NRLLQRSQSS--QRGEDGAKSIAKRLEAYHRASIPVVTYYERKT 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	74/165 (45%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	74/161 (46%)
Ak5	XP_011238417.1	ADK	134..307	CDD:238713
Ak5	XP_011238417.1	aden_kin_iso1	374..540	CDD:130427	75/171 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3944
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43577
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820