DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adk1 and AK9

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_011533852.1	Gene:	AK9 / 221264	HGNCID:	33814	Length:	1988	Species:	Homo sapiens

Alignment Length:	191	Identity:	57/191 - (29%)
Similarity:	80/191 - (41%)	Gaps:	52/191 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KEAEEKL---KAEELRRARAAADIPI-IWILGGPGCGKGT-----QCAKIVEKYGFTHLSSGDLL 67
            ||.:||.   ..:.:|:.:....:|| |.|:|.|..||.|     ...||..:||..|||.|..|
Human  1459 KETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVLCFSVAKKITSEYGLKHLSIGGAL 1523

  Fly    68 RNEVASGSDKGRQLQAVMAS----GGLVSNDEV------LSLLNDAITRAKGSSKGFLIDGYPRQ 122
            |..:.:..:  .:| |:|.:    .|:.:.||:      |||:......|     |.:|||||..
Human  1524 RYVLNNHPE--TEL-ALMLNWHLHKGMTAPDELAIQALELSLMESVCNTA-----GVVIDGYPVT 1580

  Fly   123 KNQGIEFEAR-IAPADLALYFECSEDTMVQRIMARAAASAVKRDDDNEKTIRARLLTFKQN 182
            |:|....||| |.|   .:.||.|..:                     |.|..|||..|:|
Human  1581 KHQMNLLEARSIIP---MVIFELSVPS---------------------KEIFKRLLLEKEN 1617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	52/170 (31%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	51/166 (31%)
AK9	XP_011533852.1	ADK	105..348	CDD:238713
		Ribosomal_L24e_L24	1017..1059	CDD:321242
		ADK	1065..>1233	CDD:238713
		ADK	1485..>1612	CDD:238713	46/158 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810