DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and F38B2.4

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001257141.1	Gene:	F38B2.4 / 181317	WormBaseID:	WBGene00009531	Length:	210	Species:	Caenorhabditis elegans

Alignment Length:	196	Identity:	106/196 - (54%)
Similarity:	135/196 - (68%)	Gaps:	7/196 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 AADIPIIWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVMASGGLVSN 93
            ||.:||.:|:||||.||||||.|||.|||.||||||||||:||.|||.:|.||.|:|.||.||..
Worm    17 AAGVPIFFIVGGPGSGKGTQCDKIVAKYGLTHLSSGDLLRDEVKSGSPRGAQLTAIMESGALVPL 81

  Fly    94 DEVLSLLNDAITRA--KGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMAR 156
            :.||.|:.:|:.:|  || |||||||||||:..||.:||:.|..|.|.|:|:.:|:|:|:|::.|
Worm    82 EVVLDLVKEAMLKAIEKG-SKGFLIDGYPREVAQGQQFESEIQEAKLVLFFDVAEETLVKRLLHR 145

  Fly   157 AAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEP--KTLTINAERDVDDIFLEVVQAIDCVLK 219
            |..|.  |.|||..||:.||.||..:|..:::.||.  |.:.||||..|||||..||..:|....
Worm   146 AQTSG--RADDNADTIKKRLHTFVTSTAPVVDYYESKGKLVRINAEGSVDDIFAVVVANLDKATS 208

  Fly   220 K 220
            |
Worm   209 K 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	104/190 (55%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	96/175 (55%)
F38B2.4	NP_001257141.1	aden_kin_iso1	18..206	CDD:130427	104/190 (55%)
F38B2.4	NP_001257141.1	ADK	22..195	CDD:238713	96/175 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	164	1.000	Domainoid score	I2386
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20135
Inparanoid	1	1.050	188	1.000	Inparanoid score	I2584
Isobase	1	0.950	-	0	Normalized mean entropy	S697
OMA	1	1.010	-	-		QHG54223
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	1	1.000	-	-		FOG0005806
OrthoInspector	1	1.000	-	-		oto17669
orthoMCL	1	0.900	-	-		OOG6_100591
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2590
SonicParanoid	1	1.000	-	-		X4196
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.960