DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and F13E6.2

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_509786.2	Gene:	F13E6.2 / 181264	WormBaseID:	WBGene00008746	Length:	729	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	67/243 - (27%)
Similarity:	118/243 - (48%)	Gaps:	36/243 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RVMKKEAEEKLKAEELRRAR---------------AAADI----------PIIWILGGPGCGKGT 47
            |..:...:|||...:.:.|.               :||::          |:|.:||.||..|..
Worm   464 RSRESARKEKLATPDSKNAADTRNKTSSNGSSEIVSAAELGEPVGLPNNAPVILVLGAPGSQKND 528

  Fly    48 QCAKIVEKY-GFTHLSSGDLLRNEVASGSDKGRQL----QAVMASGGLVSNDEVLSLLNDAITRA 107
            ...:|.:|| |||.||.||:||.::  .::|..::    ...|.:|..:......::|.:.:...
Worm   529 ISRRIAQKYDGFTMLSMGDILRKKI--NNEKNDEMWDKVSKKMNNGDPIPTKMCRTVLYEELHSR 591

  Fly   108 KGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMARAAASAVKRDDDNEKTI 172
            ..|:.|::|:|||:..:|.::.|..:...|||:..:|:|...::.|..|...:  ||.||:...:
Worm   592 GTSNWGYVIEGYPKSPDQLVDLEHSLQRTDLAILIDCTEQFCLEVINKRNREN--KRSDDDSDAV 654

  Fly   173 RARLLTFKQNTNAILELYEP--KTLTINAERDVDDIFLEVVQAIDCVL 218
            |:|:..||:||..:|:..:.  |...::.:.|.|.:|.||||.||..|
Worm   655 RSRMEYFKKNTLPMLKTLDDKGKLRVVDGDADPDTVFKEVVQVIDRTL 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	60/203 (30%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	51/178 (29%)
F13E6.2	NP_509786.2	aden_kin_iso1	168..355	CDD:130427
		ADK	171..337	CDD:238713
		aden_kin_iso1	514..699	CDD:130427	57/188 (30%)
		ADK	515..690	CDD:238713	51/178 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780