DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk1 and ak5

DIOPT Version :9

Sequence 1:	NP_729792.1	Gene:	Adk1 / 39396	FlyBaseID:	FBgn0022709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001093554.1	Gene:	ak5 / 100003595	ZFINID:	ZDB-GENE-030131-8256	Length:	563	Species:	Danio rerio

Alignment Length:	187	Identity:	65/187 - (34%)
Similarity:	109/187 - (58%)	Gaps:	8/187 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IIWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEV---ASGSDKGRQLQAVMASGGLVSNDE 95
            :|.|:||||.||||||.||.|:|||.::|.|:|||.::   |:.:.|...:..::.:|.|...:.
Zfish   134 VILIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSNRKWSLIARIITNGELAPQET 198

  Fly    96 VLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMARAAAS 160
            .::.:...|.:...:| |.:|||:||...|.:.||.::...||.::..||...:.:|:..||...
Zfish   199 TITEIKQKIMKIPEAS-GIVIDGFPRDVGQALSFEDQVCTPDLVVFLACSNQRLKERLEKRAEQQ 262

  Fly   161 AVKRDDDNEKTIRARLLTFKQNTNAILELYEPKTL--TINAERDVDDIFLEVVQAID 215
            .  |.|||.|.|..||..||||...:::.::.|.|  |::|:||.:::|.::...:|
Zfish   263 G--RPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVD 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	65/187 (35%)
Adk1	NP_729792.1	ADK	34..206	CDD:238713	63/176 (36%)
ak5	NP_001093554.1	aden_kin_iso1	133..317	CDD:130427	64/185 (35%)
		ADK	134..308	CDD:238713	63/176 (36%)
		aden_kin_iso1	375..562	CDD:130427
		ADK	379..552	CDD:238713
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820