Protein Alignment CG11529 and KLK6

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 75/245 - (30%)
• Similarity: 112/245 - (45%)
• Gaps: 29/245 - (11%)

  Fly    27 SYAVGQSKY---GRIEK--FPYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHCTMGVTHYDVYL 86
            ::|..|:|.   |..:|  .|||..|...    ..:||||.|:...|:|||.||..  .:..|:|
Human    14 AWAEEQNKLVHGGPCDKTSHPYQAALYTS----GHLLCGGVLIHPLWVLTAAHCKK--PNLQVFL 72

  Fly    87 GTKSVEDTEVS--GGLVLRSNKFIVHERFNPETAANDIALVKLPQDVAFTPRIQPASLPSRYRHD 149
            |..::...|.|  ...|:|:   ::|..::..:...||.|::|.:....:..|||..|    ..|
Human    73 GKHNLRQRESSQEQSSVVRA---VIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL----ERD 130

  Fly   150 QFAG-MSVVASGWGAMVEMTNSDSMQYTELKVISNAECAQEY-DVVTSGVICA---KGLKDETVC 209
            ..|. .|....|||...:....|::|...:.::|..||...| ..:|..::||   |..||.  |
Human   131 CSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS--C 193

  Fly   210 TGDSGGPLVLKDTQIVVGITSFGPADGCETNIPGGFTRVTHYLDWIESKI 259
            .||||||||..|.  :.|:.|:|.........||.:|.|..|.:||:..|
Human   194 QGDSGGPLVCGDH--LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	70/229 (31%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	69/230 (30%)