Protein Alignment CG11529 and PRSS8

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 83/272 - (30%)
• Similarity: 132/272 - (48%)
• Gaps: 46/272 - (16%)

  Fly    40 KFPYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHCTMGVTH---YDVYLGTKSV----EDTEVS 97
            ::|:||.:..:.:.    :|||:|:.::|:|:|.||.....|   |:|.||...:    ||.:||
Human    55 QWPWQVSITYEGVH----VCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVS 115

  Fly    98 GGLVLRSNKFIVHERFNPETAANDIALVKLPQDVAFTPRIQPASLPSRYRHDQFA-GMSVVASGW 161
               .|:.  .|.|..:..|.:..||||::|.:.:.|:..|:|..||:  .:..|. |:....:||
Human   116 ---TLKD--IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPA--ANASFPNGLHCTVTGW 173

  Fly   162 GAM---VEMTNSDSMQYTELKVISNAECAQEYDV---------VTSGVICA---KGLKDETVCTG 211
            |.:   |.:.....:|..|:.:||...|...|::         |...::||   :|.||  .|.|
Human   174 GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKD--ACQG 236

  Fly   212 DSGGPL--VLKDTQIVVGITSFGPADGCETNIPGGFTRVTHYLDWIESKIGSHGQVHQQYLRPQQ 274
            ||||||  .::....:.||.|:|.|.|.. |.||.:|..:.|..||:||:..    .|..:.||.
Human   237 DSGGPLSCPVEGLWYLTGIVSWGDACGAR-NRPGVYTLASSYASWIQSKVTE----LQPRVVPQT 296

  Fly   275 QHHHHQYSDNNL 286
            |   ....|:||
Human   297 Q---ESQPDSNL 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	74/242 (31%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	74/242 (31%)