Protein Alignment CG11529 and KLK7

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 82/271 - (30%)
• Similarity: 135/271 - (49%)
• Gaps: 41/271 - (15%)

  Fly     9 LLGLAVIMLMMWKPTPTDSYAVGQSKYGRIEKF-----------PYQVMLI-GKQLWRKRILCGG 61
            ||.|.:::|.:...|      .|:...|  :|.           |:||.|: |.||.     |||
Human     6 LLPLQILLLSLALET------AGEEAQG--DKIIDGAPCARGSHPWQVALLSGNQLH-----CGG 57

  Fly    62 TLLDKRWILTAGHCTMGVTHYDVYLGTKSVEDTEVSGGLVLRSNKFIVHERFNPETAANDIALVK 126
            .|:::||:|||.||.|  ..|.|:||:.::.|.....   ::::|...|..::.:|..||:.|||
Human    58 VLVNERWVLTAAHCKM--NEYTVHLGSDTLGDRRAQR---IKASKSFRHPGYSTQTHVNDLMLVK 117

  Fly   127 LPQDVAFTPRIQPASLPSRYRHDQFAGMSVVASGWGAMV--EMTNSDSMQYTELKVISNAECAQE 189
            |......:..::...||||.   :..|.:...||||...  ::|....:...::|:||..:|.:.
Human   118 LNSQARLSSMVKKVRLPSRC---EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV 179

  Fly   190 Y-DVVTSGVICAKGLKD--ETVCTGDSGGPLVLKDTQIVVGITSFGPADGCETNIPGGFTRVTHY 251
            | |::.:.::|| |:.|  :..|.||||||||.:.|  :.|:.|:|.....:.|.||.:|:|..:
Human   180 YKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKF 241

  Fly   252 LDWIESKIGSH 262
            ..||...:..|
Human   242 TKWINDTMKKH 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	74/237 (31%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	72/231 (31%)