Protein Alignment CG11529 and PRSS1

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 86/269 - (31%)
• Similarity: 128/269 - (47%)
• Gaps: 41/269 - (15%)

  Fly     9 LLGLAVIMLMMWKPTPTDSYAVGQSKYGRIE-KFPYQVMLIGKQLWRKRILCGGTLLDKRWILTA 72
            ||.|..:...:..|...|...||  .|...| ..||||.|.....:     |||:|::::|:::|
Human     4 LLILTFVAAALAAPFDDDDKIVG--GYNCEENSVPYQVSLNSGYHF-----CGGSLINEQWVVSA 61

  Fly    73 GHCTMGVTHYDVYLGTKSVEDTEVSGGLVLRSN-------KFIVHERFNPETAANDIALVKLPQD 130
            |||..  :...|.||..::|        ||..|       |.|.|.:::.:|..|||.|:||...
Human    62 GHCYK--SRIQVRLGEHNIE--------VLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSR 116

  Fly   131 VAFTPRIQPASLPSRYRHDQFAGMSVVASGWG--AMVEMTNSDSMQYTELKVISNAECAQEY-DV 192
            .....|:...|||:.   ....|...:.||||  |.......|.:|..:..|:|.|:|...| ..
Human   117 AVINARVSTISLPTA---PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGK 178

  Fly   193 VTSGVICA---KGLKDETVCTGDSGGPLVLKDTQIVVGITSFGPADGC-ETNIPGGFTRVTHYLD 253
            :||.:.|.   :|.||.  |.||||||:|....  :.|:.|:|  ||| :.|.||.:|:|.:|:.
Human   179 ITSNMFCVGFLEGGKDS--CQGDSGGPVVCNGQ--LQGVVSWG--DGCAQKNKPGVYTKVYNYVK 237

  Fly   254 WIESKIGSH 262
            ||::.|.::
Human   238 WIKNTIAAN 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	77/235 (33%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	78/241 (32%)