DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11529 and prss27

DIOPT Version :9

Sequence 1:	NP_648558.1	Gene:	CG11529 / 39395	FlyBaseID:	FBgn0036264	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	78/288 - (27%)
Similarity:	138/288 - (47%)	Gaps:	51/288 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLGLAV--IMLMMWKPTPTDSYAVGQSK-YGRIEKFPYQVMLIGKQLWRKRILCGGTLLDKRWIL 70
            |.|.||  |.....:|..:|....|.:. :|   ::|:||.::    ::...:|||:|:...|::
Frog   399 LAGFAVTAISTGCGQPAFSDRIVGGNNAVFG---EWPWQVSIV----YQNSHICGGSLVSSNWVV 456

  Fly    71 TAGHC---TMGVTHYDVYLGTKSVEDTEVSGGLVLRSNKFIVHERFNPETAANDIALVKLPQDVA 132
            :|.||   :..:.:..|.||..::.:. .|..:::|..:.|.:..:..|.::.|||:|::...|.
Frog   457 SAAHCFPRSYKIENMQVLLGCFALMNL-TSDAVIIRVKRVITYPLYTGEGSSGDIAMVEMESPVT 520

  Fly   133 FTPRIQPASLPSRYRHDQF-AGMSVVASGWGAM---VEMTNSDSMQYTELKVISNAECAQEY--- 190
            ::..|.|..:|  ..::.| :|.....:|||.:   |.::....:|..|:.:::.:.|...|
Frog   521 YSSYILPICIP--LTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCDTMYHYN 583

  Fly   191 -------DVVTSGVICA---KGLKDETVCTGDSGGPLVLKDTQ--IVVGITSFGPADGC-ETNIP 242
                   .:|...:|||   :|.||  .|.|||||||..|...  .:.||.|:|  ||| :.|.|
Frog   584 SDLNPATQLVHDDMICAGYPEGQKD--ACQGDSGGPLACKSGNYWFLTGIVSWG--DGCAQPNRP 644

  Fly   243 GGFTRVTHYLDWIESKIGSHGQVHQQYL 270
            |.:|:|:.:..||           .|||
Frog   645 GVYTKVSSFSSWI-----------NQYL 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	66/243 (27%)
CG11529	NP_648558.1	Tryp_SPc	37..255	CDD:214473	64/240 (27%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	68/263 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910