Protein Alignment CG11529 and KLK12

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 80/264 - (30%)
• Similarity: 123/264 - (46%)
• Gaps: 55/264 - (20%)

  Fly    10 LGLAVIMLMMWKPTPTDSYAVGQSKYGRIEKF----------PYQVMLI-GKQLWRKRILCGGTL 63
            :||::.:|:.         .:|.|:....:.|          |:||.|. |..|     .|||.|
Human     1 MGLSIFLLLC---------VLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSL-----RCGGVL 51

  Fly    64 LDKRWILTAGHCTMGVTHYDVYLGTKSVED---TEVSGGLVLRSNKF-IVHERFNPETAA--NDI 122
            :|.||:|||.||:  .:.|.|.||..|:..   ||     .:|.:.| :.|..:...:.:  :|:
Human    52 IDHRWVLTAAHCS--GSRYWVRLGEHSLSQLDWTE-----QIRHSGFSVTHPGYLGASTSHEHDL 109

  Fly   123 ALVKLPQDVAFTPRIQPASLPSRYRHDQFAGMSVVASGWGAMVEMTN------SDSMQYTELKVI 181
            .|::|...|..|..:||..||:   ....||.....||||    :||      .|.:|...|.::
Human   110 RLLRLRLPVRVTSSVQPLPLPN---DCATAGTECHVSGWG----ITNHPRNPFPDLLQCLNLSIV 167

  Fly   182 SNAECAQEY-DVVTSGVICAKGLKDETVCTGDSGGPLVLKDTQIVVGITSFGPADGC-ETNIPGG 244
            |:|.|...| ..:||.::||.|:..:..|.||||||||...  ::.|:.|:|....| :..|||.
Human   168 SHATCHGVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGG--VLQGLVSWGSVGPCGQDGIPGV 230

  Fly   245 FTRV 248
            :|.:
Human   231 YTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	75/237 (32%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	75/234 (32%)