Protein Alignment CG11529 and KLKB1

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 91/270 - (33%)
• Similarity: 137/270 - (50%)
• Gaps: 43/270 - (15%)

  Fly    23 TPTDSYAVG--QSKYGRIEKFPYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHCTMGVTHYDV- 84
            |.|.:..||  .|.:|   ::|:||.|..| |..:|.||||:|:..:|:|||.||..|:...||
Human   396 TKTSTRIVGGTNSSWG---EWPWQVSLQVK-LTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVW 456

  Fly    85 --YLGTKSV----EDTEVSGGLVLRSNKFIVHERFNPETAANDIALVKLPQDVAFTPRIQPASLP 143
              |.|..::    :||..|     :..:.|:|:.:......:||||:||...:.:|...:|..||
Human   457 RIYSGILNLSDITKDTPFS-----QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 516

  Fly   144 SRYRHDQFAGMSVV-----ASGWGAMVEMTN-SDSMQYTELKVISNAECAQEYD--VVTSGVICA 200
            |:      ...|.:     .:|||...|... .:.:|...:.:::|.||.:.|.  .:|..::||
Human   517 SK------GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 575

  Fly   201 ---KGLKDETVCTGDSGGPLVLKDTQI--VVGITSFGPADGC-ETNIPGGFTRVTHYLDWI-ESK 258
               :|.||  .|.||||||||.|...:  :|||||:|  :|| ....||.:|:|..|:||| |..
Human   576 GYKEGGKD--ACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEKT 636

  Fly   259 IGSHGQVHQQ 268
            ..|.|:...|
Human   637 QSSDGKAQMQ 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	82/242 (34%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519
		Tryp_SPc	402..632	CDD:238113	83/248 (33%)