Protein Alignment CG11529 and KLK11

DIOPT Version :10

• Sequence 1: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 83/253 - (32%)
• Similarity: 118/253 - (46%)
• Gaps: 55/253 - (21%)

  Fly    42 PYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHC------TMGVTH-----------------YD 83
            |:|..|..|    .|:|||.||:..||:|||.||      ....||                 |.
Human    66 PWQAALFEK----TRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYI 126

  Fly    84 VYLGTKSVEDTEVSGGLVLRSNKFIVHERFN----PETAANDIALVKLPQDVAFTPRIQPASLPS 144
            |:||..:::..|........:..| .|..||    .:...|||.|||:...|:.|..::|.:|.|
Human   127 VHLGQHNLQKEEGCEQTRTATESF-PHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSS 190

  Fly   145 RYRHDQFAGMSVVASGWGAMVEMTNS------DSMQYTELKVISNAECAQEY-DVVTSGVICA-- 200
            |.   ..||.|.:.||||:    |:|      .:::...:.:|.:.:|...| ..:|..::||
Human   191 RC---VTAGTSCLISGWGS----TSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASV 248

  Fly   201 -KGLKDETVCTGDSGGPLVLKDTQIVVGITSFGPADGCE-TNIPGGFTRVTHYLDWIE 256
             :|.||.  |.||||||||.  .|.:.||.|:| .|.|. |..||.:|:|..|:|||:
Human   249 QEGGKDS--CQGDSGGPLVC--NQSLQGIISWG-QDPCAITRKPGVYTKVCKYVDWIQ 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	83/253 (33%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	81/250 (32%)