Protein Alignment Est-P and Ces1h

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 575
• Identity: 161/575 - (28%)
• Similarity: 242/575 - (42%)
• Gaps: 113/575 - (19%)

  Fly     8 LCLTLLWIAALESEA------DPLIVEITNGKIRGKDNGLYYSYE----------SIPNAEHPTG 56
            :||..|.:.:|.:.|      .|.:|..|:||:.||    |.|.|          .:|.|:.|.|
Mouse     1 MCLYALILLSLSAMAWGGYPSSPPVVNTTHGKVLGK----YISLEGFTQPVAVFLGVPFAKPPLG 61

  Fly    57 ALRFEAPQPYSHHWTDVFNATQSPVECMQ---WNQFINE---NNK----LMGDEDCLTVSIYKP- 110
            :|||..||| ...|:.|.|||..|..|.|   ..|.:|:   |||    |...||||.:::|.|
Mouse    62 SLRFAPPQP-PEPWSFVKNATSYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPV 125

  Fly   111 ---KKPNRSSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPG 172
               |..||  .||:|.:|||..:.|..|.|...::.....::||.|.:.|...||.||||.|..|
Mouse   126 DLMKNTNR--LPVMVWIHGGGLVVGGASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSRG 188

  Fly   173 NYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALD 237
            |:|..||..||.||:.|||:|||.|.::.:.|.||||.|..:.:|....|:|...|||.||....
Mouse   189 NWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFT 253

  Fly   238 PWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSY---------VP 293
            ..:..:.......::....|| .|..||.:..||:.|...:::..::...:|..         .|
Mouse   254 SGLFMEDASSVTEQIAVTAGC-KTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYP 317

  Fly   294 FSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWID 358
            |.       |:......|.:.|.|::....|..||:.|....::.|:....::|...
Mouse   318 FL-------PTVLDGVVLPKAPEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPP-------- 367

  Fly   359 LLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESY------------WNVQR 411
              .|...|.....||.|...        ..|::.:..:.   .::|.|            |.:|
Mouse   368 --TDVKLDKKVISLFLRKLA--------YFFNIPEDGIP---VAIEKYSKGTDDPIQNRVWLLQ- 418

  Fly   412 MFTDVLFKNSVPSAIDL--HRKYGKSPVYSFVYDN-PTDSGVGQLLSNRTDVHFGTV---HGDDF 470
            :..||:|  .:||.|..  ||..| :|.|.:.:.: |:.|         :::...||   |||:.
Mouse   419 LIGDVMF--GIPSVIVSRGHRDAG-APTYMYEFQSRPSFS---------SELKPKTVTGDHGDEV 471

  Fly   471 FLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQNNVNSKEY 525
            :.:|.....|.|...:|..:||..:....:||.|       |..|.|...:..||
Mouse   472 YSVFGAPILREGSSEEEINLSKMMMKFWANFARN-------GNPNGQGLPHWPEY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	155/551 (28%)
Ces1h	NP_001357759.1	COesterase	22..546	CDD:395084	156/554 (28%)