Protein Alignment Est-P and Ces2el1

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 160/551 - (29%)
• Similarity: 254/551 - (46%)
• Gaps: 105/551 - (19%)

  Fly     1 MSIFKRLLCLTLLWIAAL--------ESEADPLIVEITNGKIRG-----KDNGL-YYSYESIPNA 51
            |:::||..||..:....|        :..|.| |.....|::||     ||..: .:::..||.|
  Rat     1 MTLYKRPGCLNAVTCGLLLLVLHVRGQDSASP-IRNTHTGQVRGSLVHVKDTDIDVHTFLGIPFA 64

  Fly    52 EHPTGALRF---EAPQPYSHHWTDVFNATQSPVECMQ-WNQFINENNKLMG--------DEDCLT 104
            :.|.|.|||   |||:|    |:.|.:||..|..|:| .|...:|:.|:|.        .||||.
  Rat    65 KPPVGPLRFAPPEAPEP----WSGVRDATSHPAMCLQNDNMMGSEDMKIMKLILPPISMSEDCLY 125

  Fly   105 VSIYKPKKPNR-SSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDR 168
            ::||.|...:. |:.||:|.:||||...|..|:|....:.....::||.|.:.||.|||.||||.
  Rat   126 LNIYAPTHAHEGSNLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQYRLGVLGFFSTGDE 190

  Fly   169 HLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSG 233
            |..||:|..||..||:|:::|||||||.|:.:.:.|.||||.|....::....:.|..|||..||
  Rat   191 HARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESG 255

  Fly   234 NALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFG 298
            ..:.|.:|.:........:..:.||...: |..|..||:.|..::|:...:   ||..:|....|
  Rat   256 VVVLPDLISRSSEMVYRIVANLSGCAAVD-SETLMQCLRGKSEAEILDINK---VFKIIPAVVDG 316

  Fly   299 PVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGG------YNAAQLLERNKLTGESWI 357
                      .||.:.|:.::.|..|.:||..:....::.|      :::||.:|  ::|.::
  Rat   317 ----------EFLPKHPQELLASANFHRVPSIIGINNDEYGWILPMIFDSAQKIE--EITRKT-- 367

  Fly   358 DLLNDRWFDWAPYLLFYRDAKKTIKDM------DDLSFDLRQQYLADRRFSVESYWNVQRMFTDV 416
                      .|.:|     |.|...|      .||   |.::|:.|    .|....:|..|.::
  Rat   368 ----------LPTVL-----KSTALKMMLPPECGDL---LMEEYMGD----TEDPKTLQAQFREM 410

  Fly   417 L--FKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDV---HFGTVHGDDFFLIFNT 476
            :  |...:|:....|.:...:|||.:.:.:.:        |...||   |....|||:.||:|
  Rat   411 MGDFMFVIPALQVAHFQRSHAPVYFYEFQHRS--------SFFKDVKPPHVKADHGDEVFLVF-- 465

  Fly   477 AAYRTG-IR----PDEEVISKKFIGMLEDFA 502
             .|..| |:    .:||::|:|.:....:||
  Rat   466 -GYLVGDIKFPHTEEEELLSRKIMKYWANFA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	152/518 (29%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	154/522 (30%)