Protein Alignment Est-P and Ces5a

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 543
• Identity: 149/543 - (27%)
• Similarity: 230/543 - (42%)
• Gaps: 106/543 - (19%)

  Fly    12 LLWI-----AALESEADPLIVEITN-----GKIRGKDNGLYYSYE------SIPNAEHPTGALRF 60
            |:|:     |.:|......:.|..:     |.::||...:....|      .||.|..|.|.|||
Mouse    12 LIWVIWIFGAIIEGAMAGSVTEEPHRYTKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRF 76

  Fly    61 EAPQPYSHHWTDVFNATQSPVECMQ---WNQFINEN-----NKLMG-DEDCLTVSIYKPKKPNR- 115
            ..||| ...|.::..||..|..|.|   | .||.:|     ..::| .||||.::||.|...|.
Mouse    77 SKPQP-PIPWDNLREATAYPNLCFQNLEW-LFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNG 139

  Fly   116 SSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQR 180
            ||.||:|.:.||.|..||.||:...::.....:|||.|.:.||..||.:|.::|.|||:...||.
Mouse   140 SSLPVMVWIPGGGFETGSASIFDGSALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQL 204

  Fly   181 LALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGG 245
            .||.|:::||.:|||.||::.:.|:|||..|....:|......|...||..||.|:.| .::...
Mouse   205 AALLWVRENIKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIP-SLKSSD 268

  Fly   246 RRRAFEL---GRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAP 307
            .....:|   ..:..|..::..|.|| ||:.|.:.:::|..:.        ..:|..||:.|
Mouse   269 NDLKHDLQVVANVCDCNVSDSKALLK-CLREKSSLELMSLSQK--------AKSFTRVVDGS--- 321

  Fly   308 DAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGY------NAAQLLERNKLTGESWIDLLNDRWFD 366
              |.:|:|..::.......||..:....::.||      ....||..|:.|..:.|..|..
Mouse   322 --FFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTPEILLGSNESTALTLIHTLLH---- 380

  Fly   367 WAP----YLLF--YRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSA 425
             .|    |::.  |...|.:..|:.|...||                     |.||.|  .||..
Mouse   381 -IPTQHLYIVTKEYFHGKHSPTDIRDTLLDL---------------------FGDVFF--VVPGL 421

  Fly   426 ID--LHRKYGKSPVYSFVYDNP----TDSGVGQLLSNRTD-VHFGTVHGDDFF----LIFNTAAY 479
            :.  .||..| .|||.:.:.:.    .:|....:.::.|| :.|  |.|..|.    ::|..|.
Mouse   422 VTARYHRDSG-GPVYFYEFQHRPHCFQNSRPAFVKADHTDEIRF--VFGGPFLKGDVVMFEEAT- 482

  Fly   480 RTGIRPDEEVISKKFIGMLEDFA 502
                 .:|:::|:|.:....:||
Mouse   483 -----EEEKLLSRKMMKYWANFA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	145/524 (28%)
		Aes	<107..>240	CDD:223730	54/133 (41%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	145/522 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940