Protein Alignment Est-P and ces2a

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 539
• Identity: 143/539 - (26%)
• Similarity: 227/539 - (42%)
• Gaps: 102/539 - (18%)

  Fly     8 LCLTL--LWIAALESEADPLIVEITNGKIRG---KDNG---LYYSYESIPNAEHPTGALRFEAPQ 64
            |||||  :|.|.::.::.|:.| :.:|.:||   |..|   :...|..||.|:.|.|..|..|||
Zfish     9 LCLTLAPVWSAPVQEDSGPVAV-LKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQ 72

  Fly    65 PYSHHWTDVFNATQSPVECMQWNQFINENNKLMG--------DEDCLTVSIYKP-KKPNRSSFPV 120
            |. ..|..:.|||:.|:.|:|....:....|.:.        .||||.:::|.| ::......||
Zfish    73 PV-QGWEGIRNATEHPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPV 136

  Fly   121 VVLLHGGAFMFGSGSIYGHDSIMREGT-------LLVVKISFGLGPLGFASTGDRHLPGNYGLKD 178
            ::.:|||....|...:: .:..:.:||       ::||.|.:.||.||:.||||:|..||:|..|
Zfish   137 MIWIHGGGLAMGGACMF-KELCLYDGTPLAAYEKVVVVVIQYRLGILGYFSTGDQHAKGNWGFLD 200

  Fly   179 QRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQ 243
            |..||||:::||..|||.|.::.:.|.||||.||.|..|....|.|.:.||..||.|.......:
Zfish   201 QIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYFVK 265

  Fly   244 GGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPD 308
            .....|..:..|..|..:: |..|..|::......|:.|.:...:|             |..|.|
Zfish   266 DPSTHAQVIANITECDFSS-SEVLVKCIREMTEEQIIKAAQKKGIF-------------PGAAVD 316

  Fly   309 A-FLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQL-LERNKLTG------ESWIDLLNDRWF 365
            . |:...|..::||..|.:||..:..|..:.|:...|: |.:..:.|      :..:.|||....
Zfish   317 GEFIKAQPEEILKSKDFQKVPILIGTTNHEFGWMLPQIFLPKEWVKGMDTKAAKDRLGLLNADGA 381

  Fly   366 DWAPYLL---FYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAID 427
            ..|..::   ::::||...:..|..:..|...::.....:|.||
Zfish   382 SGANGIIADEYFKNAKTPEEIRDAFTELLGDIFMVIPSITVASY--------------------- 425

  Fly   428 LHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTV-HGDDFFLIFNTAAYRTGIRPDEEVIS 491
             ||:.| .|||.:.:.:      |...:|:....|... |.||...:|....:
Zfish   426 -HREAG-VPVYMYEFQH------GPSTANKFRPSFVKADHADDVGFVFGACFW------------ 470

  Fly   492 KKFIGMLEDFALNDKGTLT 510
                    |..:...||||
Zfish   471 --------DVHVKGLGTLT 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	135/519 (26%)
		Aes	<107..>240	CDD:223730	53/140 (38%)
ces2a	NP_001070720.1	COesterase	21..541	CDD:278561	136/527 (26%)
		Aes	<122..346	CDD:223730	73/238 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930