Protein Alignment Est-P and cel.2

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001020344.2
• Gene: cel.2 / 565117
• ZFINID: ZDB-GENE-061110-10
• Length: 551
• Species: Danio rerio
• Alignment Length: 568
• Identity: 155/568 - (27%)
• Similarity: 235/568 - (41%)
• Gaps: 133/568 - (23%)

  Fly    32 GKIRGKDNG---LYYS--YESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVECMQWNQFIN 91
            |.::||.:.   |.|.  ::.||.|. |.|.|:...|.|   .|..|..||:....|:|.|....
Zfish    31 GMVQGKSHSVGLLRYMDVFKGIPFAA-PPGRLQKPVPHP---GWEGVLKATEYSKRCIQLNLLQT 91

  Fly    92 ENNKLMGDEDCLTVSIYKPK-KPNRSSFPVVVLLHGGAFMFGSGS--------IYGHDSIMREGT 147
            :.   ||.||||.::|:.|: |....:.||:|.::||.|:.|.|.        :|..:.|...|.
Zfish    92 DT---MGSEDCLYLNIWVPQGKTVSYNLPVMVFIYGGGFLLGGGQGANFLDNYLYDGEEIADRGN 153

  Fly   148 LLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASA 212
            ::||..::.:|.:||.||||...||||||.||..|:.|:.:||..|||.||||.:.|.|||..|.
Zfish   154 VIVVTFNYRVGSMGFLSTGDADAPGNYGLWDQHAAISWVHRNIKAFGGNPDNITIFGESAGSTSV 218

  Fly   213 HLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLK--SKP 275
            :.|::....|.|.:.|||.||.||.||.|.:..|:.|.|:.:.|||   ...:.:..||:  ...
Zfish   219 NFQIISPKNKGLIRRAISQSGVALCPWAINRNPRKFAEEIAKKVGC---PTDSGMVACLRRTDPK 280

  Fly   276 ASDIVSAVRSFLVFSYVPFSAFGPVVEP---SDAPDA-FLTEDPRAVIKSGKFAQVPW------- 329
            |..:...||       :..||..|:|..   |...|. |:.::|..:.  |..|.:.:
Zfish   281 AVTLAGKVR-------LATSATEPIVHNLYLSPVIDGDFIPDEPDTLF--GNAADIDYIAGVNDM 336

  Fly   330 ---------------AVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWA--PYLLFYRDA 377
                           |:..|||:.....|..|.::: ..::.|....:...:|.  |.   ..|.
Zfish   337 DGHIFATLDIPSINNALATTTEEEVQALATALSKDR-GQDAGIATFQEYTVNWGSKPN---KEDI 397

  Fly   378 KKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSP-VYSFV 441
            |||:.:|:                            ||.:|.....:|:.||....||. .||::
Zfish   398 KKTVVEME----------------------------TDYIFLVPTQTALYLHSDNAKSARTYSYL 434

  Fly   442 YDNPTDSGVGQLLSNRTDVH---FGTVHGDDFFLIFNTAAYRT--GIRPDEEVISKKFIGMLEDF 501
            :..          |:|..:.   .|..|.|:...:|. ..:.|  |..|....:||..|....:|
Zfish   435 FSE----------SSRIPIFPLWMGADHADELQYVFG-KPFTTPLGYFPRHRDVSKYMIAYWTNF 488

  Fly   502 ALNDKGTLTFGEC-------NFQN------NVNSKEYQVLRISRNACK 536
            |  ..|....||.       .|.|      ::|:|      |:.|:.|
Zfish   489 A--QTGNPNTGESKVPVTWPEFSNPGHQYLDINNK------INTNSVK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	155/568 (27%)
cel.2	NP_001020344.2	COesterase	26..539	CDD:395084	155/568 (27%)