Protein Alignment Est-P and alpha-Est3

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 592
• Identity: 166/592 - (28%)
• Similarity: 250/592 - (42%)
• Gaps: 129/592 - (21%)

  Fly    23 DPLIVEITNGKIRGKD-NGL----YYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVE 82
            :.|.|..|:|.:.||. .|:    |.|:|.||.|:.|.|.|||.||.|. ..|:...:.|:...:
  Fly     2 ESLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPV-EPWSQPLDCTKPGQK 65

  Fly    83 CMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGHDS---IMR 144
            .:|:|.:   :.:|.|.||||.:::|..:..:....|::|...||.|..|..:...|..   :||
  Fly    66 PLQFNHY---SKQLEGVEDCLYLNVYAKELDSPRPLPLIVFFFGGGFEKGDPTKELHSPDYFMMR 127

  Fly   145 EGTLLVVKISFGLGPLGFASTGDR--HLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSA 207
            :  ::||.:|:.:|||||.|..|.  .:|||.|||||.||::|||:|...|.|.|.|:...|.||
  Fly   128 D--VVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESA 190

  Fly   208 GGASAHLQLLHEDFKHLAKGAISVSGNALDPW---VIQQGGRRRAFELGRIVGCGHTNVSAELKD 269
            |.||.|..:|:...:.|...||..|||.|..|   .|:....|.|..|| :....|. ..|.:.|
  Fly   191 GAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLG-MESAEHV-TDAMVLD 253

  Fly   270 CLKSKPASDIVSAVRSFL----------VFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKF 324
            .|:..|...:   ||.:|          ||.      |||:|||.......|...|:.::...
  Fly   254 FLQKLPGEKL---VRPYLLSAEEHLDDCVFQ------FGPMVEPYKTEHCALPNHPQELLDKA-- 307

  Fly   325 AQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSF 389
                |.          |...:|    ::|.|:..||.......|||||  ...||..:.|  |..
  Fly   308 ----WG----------NRIPVL----MSGTSFEGLLMYARVQMAPYLL--TSLKKEPEHM--LPL 350

  Fly   390 DLRQ-----------QYLADRRF-----------SVESY--WNVQRMFTDVLFK---NSVPSAID 427
            |:::           |.|.:..|           |:::|  :...::|...:.|   :.|.|:
  Fly   351 DVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSS-- 413

  Fly   428 LHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDF-FLIFNTAAYRTGIRPDEEVIS 491
                ...:.:|.|.:|:||.:  .|.|....|...|..|.||. :|.:...:::......|.:..
  Fly   414 ----SASTYLYRFDFDSPTFN--HQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTI 472

  Fly   492 KKFIGMLEDFA----------------------LNDKGTLTFGEC-NFQNNVNS---KEYQVLRI 530
            ::.|.||..||                      ||.|..|   || |...|:..   .|.|.||:
  Fly   473 ERMIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSAL---ECLNISENIKMMELPELQKLRV 534

  Fly   531 SRNACKN 537
            ..:.|::
  Fly   535 WESVCQS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	165/587 (28%)
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	165/584 (28%)