Protein Alignment Est-P and Ces1b

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 568
• Identity: 161/568 - (28%)
• Similarity: 245/568 - (43%)
• Gaps: 138/568 - (24%)

  Fly    13 LWIAAL------------ESEADPLIVEITNGKIRGKDNGLYYSYE----------SIPNAEHPT 55
            :|:.||            .|.:.| :|:.|.|||.||    |.|.|          .:|.|:.|.
Mouse     1 MWLHALVWASLALCPIWGHSPSSP-VVDTTQGKILGK----YTSLEGFEHPVAVFLGVPFAKPPL 60

  Fly    56 GALRFEAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMGD--------------EDCLTVS 106
            |:|||..|:| :..|:.|.|||..|..|.|....:    :|:.|              ||||.::
Mouse    61 GSLRFAPPEP-AEPWSFVKNATSYPPMCSQDAVAV----QLLSDMLSTKKESIPPLFSEDCLYLN 120

  Fly   107 IYKPKKPNRSS-FPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHL 170
            ||.|....:|| .||:|.:|||..|.|..|:|...::.....::||.|.:.||..|..||||.|.
Mouse   121 IYSPADLTKSSLLPVMVWIHGGGLMTGGASLYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHS 185

  Fly   171 PGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNA 235
            .||:...||..||:|::.|||:|||.||::.:.|.||||.|..:.:|....|:|...|||.|...
Mouse   186 RGNWAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVV 250

  Fly   236 LDPWVIQQGGRRRAFELGRIV----GCGHTNVSAELKDCLKSKPASDIV---------------S 281
            |:..||...  ..|.:|.:::    ||..|: |..:..||:.|..::::               |
Mouse   251 LENIVITLD--LVACDLSQMIATVSGCNDTS-STAMVQCLRQKTENELLEITVKLEVTKVGGAAS 312

  Fly   282 AVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGY----NA 342
            |.:.....|.|    ...||.|. ||:..|.|      ||  |:.||:.|.:..::.|:    ..
Mouse   313 AKKDNTSMSTV----IDGVVLPK-APEEILAE------KS--FSTVPYIVGFNKQEFGWIIPTML 364

  Fly   343 AQLLERNKLTGESWIDLLNDRWFDWAPYLL--FYRD-----------AKKTIKDMDDLSFDLRQQ 394
            ..||...|:..|:            |..||  |:.|           .:|.::..||.:  .::.
Mouse   365 GDLLSEGKMNEET------------ASLLLRRFHSDLNISESLIPAVIEKYLRGTDDPA--KKRD 415

  Fly   395 YLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYD---NPTDSGVGQLLSN 456
            .|.|             ||:||.|  .:| |:.|.|....:.|.:::|:   .|:      .:|:
Mouse   416 LLLD-------------MFSDVFF--GIP-AVLLSRSLRDAGVSTYMYEFRYRPS------FVSD 458

  Fly   457 RTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALN 504
            :........|||:.|.:|.....:.|...:|..:||..:....:||.|
Mouse   459 KRPQTVEGDHGDEIFSVFGIPLLKEGTSEEETNLSKMVMKFWANFARN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	156/543 (29%)
Ces1b	NP_001074841.1	COesterase	22..547	CDD:395084	157/547 (29%)