Protein Alignment Est-P and Ces2e

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001157228.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 556
• Identity: 155/556 - (27%)
• Similarity: 247/556 - (44%)
• Gaps: 115/556 - (20%)

  Fly     1 MSIFKRL------LCLTLLWIAALESE--ADPLIVEITNGKIRG-----KDNGL-YYSYESIPNA 51
            |.::|.|      .|..||.:..::.:  |.| |.....|::||     ||..: .:::..||.|
Mouse     1 MPLYKLLGWLNAVACGVLLLVLHVQGQDSASP-IRNTHTGQVRGSLVHVKDTDIAVHTFLGIPFA 64

  Fly    52 EHPTGALRF---EAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMG--------------- 98
            :.|.|.|||   |||:|    |:.|.:.|..|..|:|       |:.|||
Mouse    65 KPPVGPLRFAPPEAPEP----WSGVRDGTSHPNMCLQ-------NDNLMGSEDLKMMNLILPPIS 118

  Fly    99 -DEDCLTVSIYKPKKPNR-SSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLG 161
             .||||.::||.|...:. |:.||:|.:||||...|..|:|....:.....::||.|.:.||.||
Mouse   119 MSEDCLYLNIYVPAHAHEGSNLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVAIQYRLGVLG 183

  Fly   162 FASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAK 226
            |.||||:|..||:|..||..||:|:::||.||||.||.:.:.|.||||.|....::....:.|..
Mouse   184 FFSTGDQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFH 248

  Fly   227 GAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSY 291
            |||..||.|:.|.:|..........:..:.||...| |..|..||:.|..:::::..:   ||..
Mouse   249 GAIMESGVAVLPDLISSSSEMVHRIVANLSGCAAVN-SETLMCCLRGKNEAEMLAINK---VFKI 309

  Fly   292 VPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGY------NAAQLLERNK 350
            :|....|          .||.:.|:.::.|..|..||..:....::.|:      :.||.:|  :
Mouse   310 IPGVVDG----------EFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQKIE--E 362

  Fly   351 LTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDM------DDLSFDLRQQYLADRRFSVESYWNV 409
            :|.::            .|.:|     |.|...|      .||   |.::|:.|    .|....:
Mouse   363 ITRKT------------LPAVL-----KSTALKMMLPPECGDL---LMEEYMGD----TEDPETL 403

  Fly   410 QRMFTDVL--FKNSVPSAIDLHRKYGKSPVYSFVYDN-PTDSGVGQLLSNRTDVHFGTVHGDDFF 471
            |..|.::.  |...:|:....|.:...:|||.:.:.: |:      ...:....:....|||:.|
Mouse   404 QAQFREMKGDFMFVIPALQVAHFQRSHAPVYFYEFQHRPS------FFKDFRPPYVKADHGDEIF 462

  Fly   472 LIFNTAAYRTG-----IRPDEEVISKKFIGMLEDFA 502
            |:|   .|:.|     ...:||.:|::.:....:||
Mouse   463 LVF---GYQFGNIKLPYTEEEEQLSRRIMKYWANFA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	147/523 (28%)
		Aes	<107..>240	CDD:223730	57/133 (43%)
Ces2e	NP_001157228.1	COesterase	30..538	CDD:278561	149/527 (28%)
		Aes	<128..>231	CDD:223730	46/102 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840