Protein Alignment Est-P and cest-9.1

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 124/560 - (22%)
• Similarity: 199/560 - (35%)
• Gaps: 179/560 - (31%)

  Fly     8 LCLTLLWIAALESEADPLIVEITNGKIRG-----KDNGLYYSYESIPNAEHPTGALRFEAPQ-PY 66
            |.|.:|:|...:|..   :::.:.||:||     .|....|.::|:|.|:.|.|.|||..|| |.
 Worm     5 LFLLILFIPQFQSLK---VIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPE 66

  Fly    67 SHHWTDVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMF 131
            |  |:.:.:|::....||. |.......:....||||.::|:..:|...|..||:|..||||:..
 Worm    67 S--WSGILDASKYSPACMS-NSSSTSTPQKHYSEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNL 128

  Fly   132 GSGSIYGH----DSIMREGTLLVVKISFGLGPLGFASTGDRH-LPGNYGLKDQRLALQWIKKNIA 191
            .|..::..    |....|..:.|:. :..||..|....|... |..|..|.|...||.::...|.
 Worm   129 DSAIMFNDTFILDRYAAEDVVFVIP-AVRLGVFGQLYFGPSDLLSENLFLYDAVQALSFVHSEIN 192

  Fly   192 HFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIV 256
            :|||....:..:|||:||...              .|:..| ..:||.|       :.|:  :::
 Worm   193 YFGGDSKRVTAMGHSSGGTIV--------------DALGFS-KLIDPGV-------KLFQ--QMI 233

  Fly   257 GCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKS 321
                                  ::||...|..:..|..::|. :||.....:....:.|.|
 Worm   234 ----------------------VLSATGMFGFYDMVVDNSFA-IVEKFGCYNGTKDDRPNA---- 271

  Fly   322 GKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDD 386
                               |.|::|           |.:  |..|....||..|.    ::::||
 Worm   272 -------------------NIAEML-----------DCM--RQIDGREMLLMQRH----MEEVDD 300

  Fly   387 LSFD--LR-------QQYLADRRFSVES----YWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVY 438
            ..|.  ||       ...:||.:.|..|    |...:..|.:|...|...|.|.|.
 Worm   301 RDFRSVLRGAPFLESNGKIADLKKSPPSRNLLYGTTEHEFRNVDHMNPYISGIFLD--------- 356

  Fly   439 SFVYDNPT------DSGVGQLLSNRTDVHFGTVHGDDFFLI-----FNTAAYRTGI--------- 483
               :|||.      |.   ||::|...:    ::||...:.     |:||...||.
 Worm   357 ---FDNPVAVARYYDE---QLMANLETM----INGDAAAIFICASTFSTAMANTGADVYLFETRQ 411

  Fly   484 ----------------------RPDEEVISKKFIGMLEDF 501
                                  |||.:::...:..:|.:|
 Worm   412 KPYSFHVSDMQYFVGIHREIYHRPDMDILDTFYSKLLVNF 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	119/542 (22%)
		Aes	<107..>240	CDD:223730	37/137 (27%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	119/546 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740