Protein Alignment Est-P and cest-17

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 130/521 - (24%)
• Similarity: 206/521 - (39%)
• Gaps: 121/521 - (23%)

  Fly    42 YYSYESIPNAEHPTGALRFEAPQ-----PYSHHWTDVFNATQSPVECMQWNQFINENNKLMGDED 101
            |:.:..|.....|....||:.|:     |:.:|....|.|:..|....:..:.:|.:      ||
 Worm    45 YHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCIPSLRSELEEQVNYS------ED 103

  Fly   102 CLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGH----DSIMREGTLLVVKISFGLGPLGF 162
            ||.::|..|........||:|.:|||.|.||..|:.|:    |:.:.: .::.|.|.:.||||||
 Worm   104 CLFLNIVTPPDAKEKKLPVLVFIHGGGFQFGDTSMIGYQKAADNFVSK-DIIFVSIQYRLGPLGF 167

  Fly   163 ASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKG 227
            .:|||..:|||.||.||.||||::.:.:..|||.||.|.|.|||||.||....|......||...
 Worm   168 FTTGDSEIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGAASVSALLYSPHSDHLFSQ 232

  Fly   228 AISVSGNA-----LDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFL 287
            ||.:||:.     ||..|:....:     |.:..||...: |.||:||::.:...:::.|:.|
 Worm   233 AIQLSGSIFSESNLDRNVVDDSRK-----LAKAAGCPQED-SKELRDCIEIRTVDELLDAMES-- 289

  Fly   288 VFSYVPFSAFGPVVE---PSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERN 349
            :...:|    ||..:   |....|.|..:..:...|:.|...:...|:.   :.|.:....::..
 Worm   290 IGELLP----GPRTKKFHPYFDKDFFPYDIEKMSRKAPKKRTMQGLVSL---ESGLSVLYPVKLA 347

  Fly   350 KLTG---ESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVES------ 405
            ||.|   |||.....|...|:                       :|.|...::.|...|
 Worm   348 KLLGVPKESWSTYSKDNLVDF-----------------------IRSQVAVEQEFGTASARFSGL 389

  Fly   406 ----------------YWNV-QRMFTDVLFKNSVPSAIDLHRKYG-KSPVYSFVYDNPTDSGVGQ 452
                            |.|. ..:.:|:.:.......::|..::| .:.:|...||:.|
 Worm   390 VEEFYLSGPMTGNSSFYLNAFANLLSDLQYNIPTLHEVELKLQHGWDTYLYIIDYDSET------ 448

  Fly   453 LLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQ 517
             ..:.|....|..|..:...:||                  |.|| :....|||      :..|:
 Worm   449 -TKDPTHPIKGPFHASELRYLFN------------------FNGM-DTIPFNDK------DKKFE 487

  Fly   518 N 518
            |
 Worm   488 N 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	130/521 (25%)
		Aes	<107..>240	CDD:223730	59/141 (42%)
cest-17	NP_505114.1	COesterase	20..542	CDD:278561	130/521 (25%)
		Aes	<109..>225	CDD:223730	51/116 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910