Protein Alignment Est-P and cest-35.1

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 147/627 - (23%)
• Similarity: 234/627 - (37%)
• Gaps: 216/627 - (34%)

  Fly    14 WIAALESEADPLIVEITNGKIRGK----DNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVF 74
            :::.|:.|.:..::..:.|.|||.    |:.:...|..||.|:.|.|.|||: ....:..||:
 Worm     4 FLSHLKPEHNTEVLNASCGPIRGNIYEHDDKIVDGYLGIPFAKAPIGELRFK-KSVEAEKWTE-- 65

  Fly    75 NATQSPVECMQWNQFINENNKL-------------MGDEDCLTVSIYKPK-----KPNRSSFPVV 121
                 |::|.::.....::..|             ..:::|||::::.||     .||  ..||:
 Worm    66 -----PLDCYKYGPGCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPN--GLPVI 123

  Fly   122 VLLHGGAFMFGSGSIYGHDSIMREGTL-----LVVKISFGLGPLGFASTGDRHLPGNYGLKDQRL 181
            |..:||.|..|..|::  |.....|||     ::|..::.:|||||.:|||....||:||.||.|
 Worm   124 VYFYGGGFEVGFSSMF--DDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVSRGNWGLWDQAL 186

  Fly   182 ALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGA-------ISVSGNALDPW 239
            ||||::|:|..|||.|.|:.:.|.||||||.       ||..|:..|       |.:||.|..|:
 Worm   187 ALQWVQKHIKSFGGDPSNVTISGTSAGGASV-------DFLSLSPHANKYFHKFIPMSGAATCPF 244

  Fly   240 VIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSF-------------LVFSY 291
            .|                              :||....::  .|.|             |:..|
 Worm   245 GI------------------------------RSKDVEGLI--FREFAKHHGYAGNDSESLLHWY 277

  Fly   292 VPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESW 356
                      :..|| :.||..:......||.|:.||      ..||.:......|..|
 Worm   278 ----------QSQDA-EIFLKAEGFKYPASGMFSFVP------NYDGDFFPKPFDELRK------ 319

  Fly   357 IDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFD----------------LRQQYLADR----RF 401
                      .||.|    ||..::.:.:.|.|:                |..:.:.:|    :.
 Worm   320 ----------EAPKL----DAIVSVAEYEGLGFEEFYPGQKSPQEVLTAALGPEVVRNREEVVKK 370

  Fly   402 SVESYW-NVQ------------RMFTDVLFKNSVPSAIDLHRKYGKSPVY--SFVYDNPTDSGVG 451
            :||:|. |::            .:|.|..|...|...:....|||.: ||  ||.|.||
 Worm   371 AVEAYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGNN-VYLSSFNYFNP------ 428

  Fly   452 QLLSNRTDVHFG-------TVHGDDFFLIFN----------------TAAYRTGI----RPDEEV 489
                 .|.:.||       ..||.|...|..                ...|.|..    .|:.:.
 Worm   429 -----ETPIMFGENRPFNAASHGCDIRYILGDGIGEFSKEDRKVMDMMGTYLTNFAKYGNPNGKG 488

  Fly   490 ISKKFIGMLEDFALNDKG---TLTFGECNFQNNVNSKEYQVL 528
            :|..:    |.::|::.|   .:.:.:|...:|.....|:::
 Worm   489 VSIPW----EKYSLDNPGRYFKIDYPKCEMADNFLDGRYKII 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	145/615 (24%)
		Aes	<107..>240	CDD:223730	59/149 (40%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	143/605 (24%)
		Aes	<106..>214	CDD:223730	46/111 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740