Protein Alignment Est-P and cest-32

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 143/577 - (24%)
• Similarity: 224/577 - (38%)
• Gaps: 155/577 - (26%)

  Fly    14 WIAALESEADPLIVEITN-------GKIRGKDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWT 71
            :::.|:.||.   :|:.|       |.|...|:.:...|..||.|:.|...|||:.|.. :..||
 Worm     4 FLSHLKPEAS---LEVLNASCGPVIGNIYRHDDKIVNGYLGIPFAKAPICELRFKKPVE-AEKWT 64

  Fly    72 DVFNATQSPVECMQWNQFINE----NNKLMGDEDCLTVSIYKP-----KKPNRSSFPVVVLLHGG 127
            ...|..:....|.|....|:.    ..:...:::||.::|:.|     :.||  ..|::|..|||
 Worm    65 KPLNCHKYGPGCPQSGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPN--GLPIMVYFHGG 127

  Fly   128 AFMFGSGSIYGHDSIMREGTL-----LVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIK 187
            .|..|..|::  |.....|||     :||..::.:|||||.:|||....|||||.||.|||:|::
 Worm   128 GFEIGFSSMF--DDYSLSGTLPLKDVIVVTANYRVGPLGFMTTGDEVSRGNYGLWDQTLALKWVQ 190

  Fly   188 KNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFEL 252
            ::|..|||.|:.:.:.|.||||.||.|..|......|....:::||:|...:.|:.  :.:..|:
 Worm   191 EHIKSFGGNPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRT--KEQEAEI 253

  Fly   253 GRIVGCGH---TNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTED 314
            .|.....|   ...|..|.:..||:                  |.|.|............|||..
 Worm   254 FRNFAKHHGYEGEDSESLLEWYKSQ------------------PLSKFQETATFEKKASGFLTFI 300

  Fly   315 PRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKK 379
            |..   .|.|...|:                   ::|:.|             ||.|    ||..
 Worm   301 PNF---DGDFFPKPF-------------------DELSRE-------------APKL----DAMA 326

  Fly   380 TIKDMDDLSF------------DLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKY 432
            |:.:.:.|.|            .::..:.:|   .||:..:||:...:...||     ||   |.
 Worm   327 TVDEYEGLGFLTMFQSRRNDMDIIKSSFGSD---VVENAVDVQKRIMEFYMKN-----ID---KN 380

  Fly   433 GKSPVYSFVYDNPTDS--GVGQLLSNRTDVHFGT---VHGDDFFLIFNTAAYRT----------- 481
            ....|...:....:||  .:|.|.:.:|...:|:   :...|::.:.:...|.|
 Worm   381 DDKAVEKRLIQLISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPFKAANHGS 445

  Fly   482 --------GIRPDEEVISKKFIGMLEDFALND-KGTLTFGECNF-----QNNVNSKE 524
                    |:        .||..:.|:|.:.| .||||   .||     .|.:|..|
 Worm   446 ELKYMLGEGM--------GKFSPIEEEFKVIDMMGTLT---ANFVKYGNPNGINGPE 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	140/565 (25%)
		Aes	<107..>240	CDD:223730	55/142 (39%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	140/563 (25%)
		Aes	<104..>227	CDD:223730	51/126 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157210
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740